Results 71 to 80 of about 3,363,784 (294)

Biomarkers in bladder cancer

Histopathology, 2010
Proctor I, Stoeber K & Williams G H
(2010) Histopathology 57, 1–13
Biomarkers in bladder cancerCancer biomarkers provide an opportunity to diagnose tumours earlier and with greater accuracy. They can also identify those patients most at risk of disease recurrence and predict which tumours will respond to different therapeutic approaches.
Proctor, Ian, Stoeber, Kai, Williams, Gareth   +2 more
openaire   +3 more sources

The role of AIMP3, a putative tumour suppressor gene, as a predictive biomarker of response to chemo/radiotherapy in vitro and in patients with muscle-invasive bladder cancer. [PDF]

, 2015
Bladder cancer is the second most common urological cancer after prostate cancer and is one of the leading causes of cancer mortality in most western countries.
Gurung, PMS
core  

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

Advanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song, Yan‐Lai Tang, Xiaoting Liu, Jiayi Zheng, Chong Wu, Tang Li, Junhong Ye, Dianmin Xia, Yong Mei, Jingxuan Ma, Libin Huang, Xuequn Luo, Liheng Chen, Yanlin Qin, Weiling He   +14 more
wiley   +1 more source

Molecular profiling of bladder cancer xenografts defines relevant molecular subtypes and provides a resource for biomarker discovery.

Translational Oncology
Bladder cancer (BLCA) genomic profiling has identified molecular subtypes with distinct clinical characteristics and variable sensitivities to frontline therapy. BLCAs can be categorized into luminal or basal subtypes based on their gene expression.
Sharada Mokkapati, Ganiraju Manyam, Alexis R. Steinmetz, Côme Tholomier, Alberto Martini, Woonyoung Choi, Bogdon Czerniak, Byron H Lee, Colin P Dinney, David J McConkey   +9 more
doaj   +1 more source

Modulated Raman spectroscopy for enhanced identification of bladder tumor cells in urine samples [PDF]

, 2011
Standard Raman spectroscopy (SRS) is a noninvasive technique that is used in the biomedical field to discriminate between normal and cancer cells.
Herrington, C Simon, Briscoe, Tina, Andrew C. Riches, Sargeant, Harry, Canetta, Elisabetta, Riches, Andrew C., Sam Neilson, Dholakia, Kishan, Carruthers, Antonia Erika, Anna Chiara De Luca, Kishan Dholakia, Herrington, C. Simon, C. Simon Herrington, Elisabetta Canetta, Antonia E. Carruthers, De Luca, Anna Chiara, Carruthers, Antonia E., Neilson, Sam, Michael Mazilu, Harry Sargeant, Mazilu, Michael, Tina Briscoe, Riches, Andrew Clive   +22 more
core   +1 more source

Mitigating Cancer Therapy–Related Cognitive Impairment by Targeted Activation of Undruggable Phosphatase

Advanced Science, EarlyView.
An RVG‑engineered exosomal saRNA delivery system (RVG‑EVs‑saPtpro) effectively targets and activates hippocampal PTPRO, functioning as a “molecular brake” to alleviate cancer therapy‑related cognitive impairment (CTRCI) by enhancing neuronal survival, neurogenesis, and synaptic plasticity.
Zhimeng Yao, Yuhua Meng, Huanyi Li, Yinhui Jiang, Xiaona Lin, Mengyuan Hu, Qing Liu, Xiaofu Qiu, Hongzheng Ren, Yunlong Pan, Bin Pan, Zexiong Guo, Shuyao Zhang, Dianzheng Zhang, Li Yang, Shegan Gao, Weijing Deng, Jianfan Chen, Hao Zhang   +18 more
wiley   +1 more source

Bladder-sparing chemoradiotherapy combined with immune checkpoint inhibition for locally advanced urothelial bladder cancer—a review

, 2021
Despite current treatment strategies, the 5-year overall survival of muscle-invasive bladder cancer (MIBC) is approximately 50%. Historically, radical cystectomy (RC) with neoadjuvant chemotherapy has been the first-choice treatment for this patient ...
de Reijke, Theo M., Bins, Adriaan D., Ben-Max de Ruiter, Oddens, Jorg R., Adriaan D. Bins, Theo M. de Reijke, van Hattum, Jons W., Jorg R. Oddens, Maarten C. C. M. Hulshof, de Ruiter, Ben-Max, Hulshof, Maarten C. C. M., Jons W. van Hattum   +11 more
core   +1 more source

DIXDC1 Promotes Lymphatic Metastasis and Resistance to Cuproptosis in Bladder Cancer Through Mediating DLAT. [PDF]

Adv Sci (Weinh)
DIXDC1 drives bladder cancer progression by binding and stabilizing DLAT. This axis enhances NEK7 and CCNE2 mRNA stability to promote proliferation and lymphatic metastasis, while limiting copper‐induced DLAT oligomerization to reduce cuproptosis sensitivity, identifying DIXDC1 as a potential target linking metastasis with cuproptosis resistance ...
Li H, Cheng L, Lu X, Dong H, Fu S, Shi H, Liu M, Yang C, Huang Y, Chen Z, Zhang Y, Jie K, Zhang X, Kui X, Ye X, Chen S, Chen X, Wang H.   +17 more
europepmc   +2 more sources

The Mind From Within: Visceral Roots of Human Cognition

Advanced Science, EarlyView.
The physiological activity of visceral organs, such as the heart, the lungs, and the gut, is surprisingly linked to many sophisticated mental operations, such as remembering the past, being aware of ourselves, making choices, and forging social bonds.
Alessandro Monti, Salvatore Maria Aglioti   +1 more
wiley   +1 more source

Impact of the Level of Urothelial Carcinoma Involvement of the Prostate on Survival after Radical Cystectomy

Bladder Cancer, 2017
Objective: Urothelial prostatic involvement (UPI) at the time of radical cystoprostatectomy (RCP) was found associated with worse survival outcomes by several previous reports.
Marco Moschini, Francesco Soria, Martin Susani, Stephan Korn, Alberto Briganti, Morgan Roupret, Christian Seitz, Killian Gust, Andrea Haitel, Francesco Montorsi, Gregory Wirth, Brian D. Robinson, Pierre I. Karakiewicz, Mehmet Özsoy, Michael Rink, Shahrokh F. Shariat   +15 more
doaj   +1 more source