Results 81 to 90 of about 3,363,784 (294)

WT1‐Targeted Oral Bifidobacterium longum Vaccine Enhances Checkpoint Blockade Efficacy in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Oral WT1‐targeted Bifidobacterium longum vaccine promotes WT1‐associated cellular immunity and enhances anti‐PD‐1/anti‐CTLA‐4 efficacy in pancreatic cancer. ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains largely unresponsive to immune checkpoint inhibitors (ICI) due to its profoundly immunosuppressive tumor microenvironment.
Taiki Yamazaki   +7 more
wiley   +1 more source

The experience of UK patients with bladder cancer during the second wave of the COVID‐19 pandemic

open access: yesBJUI Compass, 2022
Beth Russell   +13 more
doaj   +1 more source

Evaluation of Intraoperative Versus Postoperative Adjuvant Mitomycin C with Nephroureterectomy for Urothelial Carcinoma of the Upper Urinary Tract

open access: yesBladder Cancer, 2018
Background: Results of randomized trials support a single dose of intravesical chemotherapy following radical nephroureterectomy (RNU) for urothelial carcinoma.
Blake Noennig   +5 more
doaj   +1 more source

The influence of glutathione S-transferases M1 and M3 on the development of bladder cancer [PDF]

open access: yes
Problem: Cigarette smoking is the most important risk factor of transitional cell carcinoma of the urinary bladder. The effect of the glutathione S- transferases M1 (GSTM1) and M3 (GSTM3) on the influence of this risk factor was investigated.
Golka, Klaus   +3 more
core  

A novel oncogenic protein in the Progranulin\EphA2 axis: the role of Myoferlin in bladder cancer

open access: yes, 2022
reservedThe growth factor progranulin plays a key role in bladder cancer by promoting cell motility and invasion. Until recently, the progranulin signaling receptor remained unknown precluding a full comprehension of progranulin action in cancer.
RUGGIERO, VALENTINA
core  

Targeted Delivery of Indole‐3‐Pyruvic Acid Suppresses Macrophage Ferroptosis to Enhance CD8+ T Cell‐Mediated Immunotherapy Response in Bladder Cancer

open access: yesAdvanced Science, EarlyView.
A microbiota‐derived metabolite, indole‐3‐pyruvic acid, suppresses macrophage ferroptosis through the AHR–NF‐κB–SLC7A11 axis. This preserves CD8+ T cell function in bladder cancer. Macrophage‐targeted nanoparticles enhance indole‐3‐pyruvic acid delivery and overcome resistance to PD‐1 blockade.
Jianwen Lao   +15 more
wiley   +1 more source

The Prognostic Value of Cell Cycle Gene Expression Signatures in Muscle Invasive, High-Grade Bladder Cancer

open access: yesBladder Cancer, 2015
Background: Approximately half of patients with muscle invasive bladder cancer succumb to their disease. Previous work identified cell cycle related genes as a prognostic class of gene expression biomarkers in bladder cancer and found a specific 31-gene ...
Garrett M. Dancik, Dan Theodorescu
doaj   +1 more source

Low Frequency of Intratumor Heterogeneity in Bladder Cancer Tissue Microarrays [Elektronisk resurs]

open access: yes, 2018
Background: Intratumoral heterogeneity (ITH) is associated with clinical challenges such as possible differences in response to treatment and difficulties in classifying the tumor.
Liedberg, Fredrik,   +5 more
core   +1 more source

Psychological Stress Associated Bile Acid Reprogramming Promotes Hepatocellular Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng   +10 more
wiley   +1 more source

Micropapillary Bladder Cancer: Insights from the National Cancer Database

open access: yesBladder Cancer, 2016
Introduction: Micropapillary bladder cancer (MPBC) is a variant histology of urothelial carcinoma (UC) that is associated with poor outcomes however given its rarity, little is known outside of institutional reports.
Wilson Sui   +7 more
doaj   +1 more source

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