TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells
Journal of Translational Medicine, 2023 Background Bladder cancer is one of the most common malignant tumors of the urinary system and is associated with a poor prognosis once invasion and distant metastases occur.
Qinrong Ping +21 more
doaj +1 more source
Evaluation of MMP‑2, MMP‑9, TIMP‑1, TIMP‑2, NGAL and MMP‑9/NGAL complex in urine and sera from patients with bladder cancer [PDF]
, 2015 The identification of biomarkers in urine or serum samples from patients with bladder cancer is urgently required for the development of non-invasive methods for the diagnosis of bladder carcinoma and to facilitate follow-up surveillance, to combat the ...
Bruzzese, Dario +2 more
core +1 more source
Is the bladder filling protocol for prostate cancer patients undergoing radiotherapy fit for purpose? (Abstract only) [PDF]
, 2020 Introduction: Conventional radiotherapy has been planned with a full bladder based on the rationale that it will move the small bowel out of the treatment field and result in greater sparing of the bladder itself[1].
Burns, Donna +2 more
core +1 more source
CircLIFR synergizes with MSH2 to attenuate chemoresistance via MutSα/ATM-p73 axis in bladder cancer
Molecular Cancer, 2021 Background Cisplatin (CDDP) has become a standard-of-care treatment for muscle-invasive bladder cancer (MIBC), while chemoresistance remains a major challenge. Accumulating evidence indicates that circular RNAs (circRNAs) are discrete functional entities.
Hui Zhang +10 more
semanticscholar +1 more source
Circulating Tumor Cells Identify Patients with Super-High-Risk Non-Muscle-Invasive Bladder Cancer: Updated Outcome Analysis of a Prospective Single-Center Trial [PDF]
, 2019 Clinical behavior of non-muscle-invasive bladder cancer (NMIBC) is largely unpredictable, and even patients treated according to European Association of Urology recommendations have a heterogeneous prognosis.
Busetto, Gian Maria +9 more
core +1 more source
Genetic and Epigenetic Alterations in Bladder Cancer [PDF]
International Neurourology Journal, 2016 Bladder cancer is one of the most common cancers worldwide, with a high rate of recurrence and poor outcomes as a result of relapse. Bladder cancer patients require lifelong invasive monitoring and treatment, making bladder cancer one of the most ...
Hong-Tao Li +3 more
doaj +1 more source
Recent patterns of bladder cancer incidence and mortality: a global overview [PDF]
World Cancer Research Journal, 2020 OBJECTIVE: Bladder cancer is the twelfth leading cancer and the fifteenth leading cancer-causing death worldwide. The present study was conducted to investigate recent patterns of bladder cancer incidence and mortality worldwide.
M. Mohammadian +8 more
doaj +1 more source
Bladder-cancer-associated mutations in RXRA activate peroxisome proliferator-activated receptors to drive urothelial proliferation [PDF]
, 2017 RXRA regulates transcription as part of a heterodimer with 14 other nuclear receptors, including the peroxisome proliferator-activated receptors (PPARs).
Arora, Vivek K +7 more
core +2 more sources
Multifunctional targeting micelle nanocarriers with both imaging and therapeutic potential for bladder cancer. [PDF]
, 2012 BackgroundWe previously developed a bladder cancer-specific ligand (PLZ4) that can specifically bind to both human and dog bladder cancer cells in vitro and in vivo. We have also developed a micelle nanocarrier drug-delivery system.
de Vere White, Ralph +8 more
core +2 more sources
Advances in diagnosis and treatment of bladder cancer
British medical journalBladder cancer remains a leading cause of cancer death worldwide and is associated with substantial impacts on patient quality of life, morbidity, mortality, and cost to the healthcare system.
A. López-Beltran +3 more
semanticscholar +1 more source