Enfortumab vedotin (EV) is an antibody-drug conjugate approved for the treatment of refractory advanced urothelial cancer. Cutaneous toxicity is well described but has not been correlated with response.
Evangelia Vlachou+6 more
doaj
Summary and Recommendations from the National Cancer Institute’s Clinical Trials Planning Meeting on Novel Therapeutics for Non-Muscle Invasive Bladder Cancer [PDF]
The NCI Bladder Cancer Task Force convened a Clinical Trials Planning Meeting (CTPM) Workshop focused on Novel Therapeutics for Non-Muscle Invasive Bladder Cancer (NMIBC).
Abrams+114 more
core +3 more sources
Epidemiology of Bladder Cancer [PDF]
Based on the latest GLOBOCAN data, bladder cancer accounts for 3% of global cancer diagnoses and is especially prevalent in the developed world. In the United States, bladder cancer is the sixth most incident neoplasm. A total of 90% of bladder cancer diagnoses are made in those 55 years of age and older, and the disease is four times more common in ...
Adam Barsouk+5 more
openaire +3 more sources
Knockdown of CDCA8 inhibits the proliferation and enhances the apoptosis of bladder cancer cells [PDF]
Bladder cancer is a tumour of the urinary system with high mortality, and there is also a great lack of therapeutic targets in the clinic. Cell division cycle associated 8 (CDCA8), an important component of the vertebrate chromosomal passenger complex ...
Xin Gao+11 more
doaj +2 more sources
Optimizing SMS Reminder Campaigns for Pre- and Post-Diagnosis Cancer Check-Ups using Socio-Demographics: An In-Silco Investigation Into Bladder Cancer [PDF]
Timely pre- and post-diagnosis check-ups are critical for cancer patients, across all cancer types, as these often lead to better outcomes. Several socio-demographic properties have been identified as strongly connected with both cancer's clinical dynamics and (indirectly) with different individual check-up behaviors.
arxiv
Cystomanometry – One of the Assessment Methods of the Urodynamic Indexes in Patients with Infiltrative Cervical Cancer [PDF]
Aim: To evaluate contractile function of urinary bladder in patients with infiltrative cervical cancer after nerve-sparing radical hysterectomy (NSRH).Patients and Methods: Ninety patients with infiltrative cervical cancer were treated with nerve-sparing
Dermenzhy, T. (Tetyana)+4 more
core +2 more sources
Multi-region segmentation of bladder cancer structures in MRI with progressive dilated convolutional networks [PDF]
Precise segmentation of bladder walls and tumor regions is an essential step towards non-invasive identification of tumor stage and grade, which is critical for treatment decision and prognosis of patients with bladder cancer (BC). However, the automatic delineation of bladder walls and tumor in magnetic resonance images (MRI) is a challenging task ...
arxiv +1 more source
Bladder-cancer-associated mutations in RXRA activate peroxisome proliferator-activated receptors to drive urothelial proliferation [PDF]
RXRA regulates transcription as part of a heterodimer with 14 other nuclear receptors, including the peroxisome proliferator-activated receptors (PPARs).
Arora, Vivek K+7 more
core +2 more sources
MiR‐490‐3p is regarded as a tumor suppressor in many cancers, but whether miR‐490‐3p is involved in the development of bladder cancer remains unknown. BALB/c nude mice (male, 15–20 g) were used to investigate the role of MiR‐490‐3p in bladder cancer. The
Cun‐Ming Zhang+4 more
doaj +1 more source
Inhibition of urothelial carcinoma through targeted type I interferon-mediated immune activation
Type I interferon (IFN-I) has potent anti-tumor effects against urothelial carcinoma (UC) and may be an alternative treatment option for patients who do not respond to Bacillus Calmette-Guerin.
Devin Plote+11 more
doaj +1 more source