Results 71 to 80 of about 5,312,533 (302)

E3 ubiquitin ligases and deubiquitinases in bladder cancer tumorigenesis and implications for immunotherapies

Frontiers in Immunology, 2023
With the rapidly increasing incidence of bladder cancer in China and worldwide, great efforts have been made to understand the detailed mechanism of bladder cancer tumorigenesis.
Maoyu Wang, Zhensheng Zhang, Zhizhou Li, Yasheng Zhu, Yasheng Zhu, Chuanliang Xu   +5 more
doaj   +1 more source

Comparison and combination of mutation and methylation-based urine tests for bladder cancer detection

Biomarker Research
Background and aims Several non-invasive tests for detecting bladder cancer (BC) are commercially available and are based on detecting small panels of BC-associated mutations and/or methylation changes in urine DNA. However, it is not clear which type of
Naheema S. Gordon, Elspeth K. McGuigan, Michaela Ondasova, Jennifer Knight, Laura A. Baxter, Sascha Ott, Robert K. Hastings, Maurice P. Zeegers, Nicholas D. James, K. K. Cheng, Anshita Goel, Minghao Yu, Roland Arnold, Richard T. Bryan, Douglas G. Ward   +14 more
doaj   +1 more source

Inhibition of urothelial carcinoma through targeted type I interferon-mediated immune activation

OncoImmunology, 2019
Type I interferon (IFN-I) has potent anti-tumor effects against urothelial carcinoma (UC) and may be an alternative treatment option for patients who do not respond to Bacillus Calmette-Guerin.
Devin Plote, Woonyoung Choi, Sharada Mokkapati, Debasish Sundi, James E Ferguson, Jon Duplisea, Nigel R. Parker, Seppo Yla-Herttuala, SUO CTC Bladder Committee, David McConkey, Kimberly S. Schluns, Colin P. Dinney   +11 more
doaj   +1 more source

The global burden of urinary bladder cancer: an update

World journal of urology, 2019
Bladder cancer is among the top ten most common cancer types in the world, with approximately 550,000 new cases annually. The highest burden of bladder cancer is currently falling on most developed communities across the globe.
A. Richters, K. Aben, L. Kiemeney
semanticscholar   +1 more source

Schistosomiasis and Urinary Bladder Cancer in North Western Tanzania: A Retrospective Review of 185 Patients. [PDF]

, 2013
Worldwide, cancers of the urinary bladder are well known to be associated with environmental chemical carcinogens such as smoking and occupational exposure to polycyclic aromatic hydrocarbons.
A Yosry, AH Zarzour, AJ Fulford, AS Felix, B Diao, CC Guo, CF Heyns, DMPP Parkin, DMWS Parkin, E Jacobo, H Abol-Enein, H Dietrich, HK Salem, I Gouda, IA Mungadi, JNLP Kitinya, JO Thomas, Kahima Jackson, KM Badr, M El-Sebaie, MJ Hess, MM Koraitim, MN El-Bolkainy, MS Zaghloul, NG El-Mawla, Peter Fabian Rambau, Philipo L Chalya, R Gonzalez Resina, RM Cooppan, RS Barsoum, SA Fedewa, SA Sheweita   +31 more
core   +1 more source

Achieving equal and timely access to innovative anticancer drugs in the European Union (EU): summary of a multidisciplinary CECOG-driven roundtable discussion with a focus on Eastern and South-Eastern EU countries

ESMO Open, 2019
The Central European Cooperative Oncology Group (CECOG) and ‘ESMO Open—Cancer Horizons’ roundtable discussion brought together stakeholders from several European Union (EU) countries involved in drug development, drug authorisation and reimbursement or ...
Nils Wilking, Anna Bucsics, Lidlija Kandolf Sekulovic, Gisela Kobelt, Andrea Laslop, Lydia Makaroff, Alexander Roediger, Christoph Zielinski   +7 more
doaj   +1 more source

Genetic variation in Glutathione S-Transferase Omega-1, Arsenic Methyltransferase and Methylene-tetrahydrofolate Reductase, arsenic exposure and bladder cancer: a case–control study [PDF]

, 2012
Background Ingestion of groundwater with high concentrations of inorganic arsenic has been linked to adverse health outcomes, including bladder cancer, however studies have not consistently observed any elevation in risk at lower concentrations.
Beebe-Dimmer, Jennifer L, Cooney, Kathleen A, Iyer, Priyanka T, Keele, Greg R, Lange, Ethan M, Mehta, Shilpin, Meliker, Jaymie R, Nriagu, Jerome O, Schottenfeld, David, Schwartz, Ann G, Zuhlke, Kimberly A   +10 more
core   +3 more sources

METTL3 promote tumor proliferation of bladder cancer by accelerating pri-miR221/222 maturation in m6A-dependent manner

Molecular Cancer, 2019
METTL3 is known to be involved in all stages in the life cycle of RNA. It affects the tumor formation by the regulation the m6A modification in the mRNAs of critical oncogenes or tumor suppressors.
Jie Han, Jing-zi Wang, Xiao Yang, Hao Yu, R. Zhou, Hongcheng Lu, Wenbo Yuan, Jiancheng Lu, Zi-jian Zhou, Q. Lu, Ji-Fu Wei, Haiwei Yang   +11 more
semanticscholar   +1 more source

circRIP2 accelerates bladder cancer progression via miR-1305/Tgf-β2/smad3 pathway

Molecular Cancer, 2020
Increasing evidences indicate that circular RNAs exert critical function in regulating bladder cancer progression. However, the expressive patterns and roles of circular RNAs in bladder cancer remain less investigated.
Yinjie Su, Weilian Feng, Juanyi Shi, Luping Chen, Jian Huang, Tianxin Lin   +5 more
semanticscholar   +1 more source

circGprc5a Promoted Bladder Oncogenesis and Metastasis through Gprc5a-Targeting Peptide

Molecular Therapy: Nucleic Acids, 2018
Bladder cancer is a serious cancer in the world, especially in advanced countries. Bladder cancer stem cells (CSCs) drive bladder tumorigenesis and metastasis. Circular RNAs (circRNAs) are involved in many biological processes, but their roles in bladder
Chaohui Gu, Naichun Zhou, Zhiyu Wang, Guanru Li, Yipping Kou, Shunli Yu, Yongjie Feng, Long Chen, Jinjian Yang, Fengyan Tian   +9 more
doaj   +1 more source