Results 81 to 90 of about 5,263,232 (399)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Achieving equal and timely access to innovative anticancer drugs in the European Union (EU): summary of a multidisciplinary CECOG-driven roundtable discussion with a focus on Eastern and South-Eastern EU countries

ESMO Open, 2019
The Central European Cooperative Oncology Group (CECOG) and ‘ESMO Open—Cancer Horizons’ roundtable discussion brought together stakeholders from several European Union (EU) countries involved in drug development, drug authorisation and reimbursement or ...
Nils Wilking, Anna Bucsics, Lidlija Kandolf Sekulovic, Gisela Kobelt, Andrea Laslop, Lydia Makaroff, Alexander Roediger, Christoph Zielinski   +7 more
doaj   +1 more source

Transurethral resection and surveillance of bladder cancer supported by 5-aminolevulinic acid-induced fluorescence endoscopy [PDF]

, 1999
Purpose: We determined whether neoplastic disease, which was missed under white light can be found during transurethral resection of bladder cancer by 5-aminolevulinic acid-induced porphyrin fluorescence.
Baumgartner, Reinhold, Hofstetter, Alfons, Knüchel, Ruth, Kriegmair, Martin, Stepp, Helmut, Stepp, Herbert, Zaak, Dirk   +6 more
core   +1 more source

circRIP2 accelerates bladder cancer progression via miR-1305/Tgf-β2/smad3 pathway

Molecular Cancer, 2020
Increasing evidences indicate that circular RNAs exert critical function in regulating bladder cancer progression. However, the expressive patterns and roles of circular RNAs in bladder cancer remain less investigated.
Yinjie Su, Weilian Feng, Juanyi Shi, Luping Chen, Jian Huang, Tianxin Lin   +5 more
semanticscholar   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

circGprc5a Promoted Bladder Oncogenesis and Metastasis through Gprc5a-Targeting Peptide

Molecular Therapy: Nucleic Acids, 2018
Bladder cancer is a serious cancer in the world, especially in advanced countries. Bladder cancer stem cells (CSCs) drive bladder tumorigenesis and metastasis. Circular RNAs (circRNAs) are involved in many biological processes, but their roles in bladder
Chaohui Gu, Naichun Zhou, Zhiyu Wang, Guanru Li, Yipping Kou, Shunli Yu, Yongjie Feng, Long Chen, Jinjian Yang, Fengyan Tian   +9 more
doaj   +1 more source

Differential Protein Expression Patterns of HOXA13 and HOXB13 Are Associated with Bladder Cancer Progression

Diagnostics, 2023
Bladder cancer is a common urological cancer and has the highest recurrence rate of any cancer. The aim of our study was to profile and characterize the protein expression of homeobox A13 (HOXA13) and homeobox B13 (HOXB13) genes in Malaysian bladder ...
Fee-Wai Chin, Huzlinda Hussin, De-Ming Chau, Teng-Aik Ong, Rosna Yunus, Azad Hassan Abdul Razack, Khatijah Yusoff, Soon-Choy Chan, Abhi Veerakumarasivam   +8 more
doaj   +1 more source

Long-Term Experience of Chemoradiotherapy Combined with Deep Regional Hyperthermia for Organ Preservation in High-Risk Bladder Cancer (Ta, Tis, T1, T2). [PDF]

, 2019
BackgroundThe aim of this study was to evaluate the efficacy and safety of chemoradiotherapy (RCT) combined with regional deep hyperthermia (RHT) of high-risk bladder cancer after transurethral resection of bladder tumor (TUR-BT).Materials and ...
Bertz, Simone, Fietkau, Rainer, Gall, Christine, Haderlein, Marlen, Hartmann, Arndt, Keck, Bastian, Kühn, Reinhard, Merten, Ricarda, Ott, Oliver, Rödel, Claus Michael, Uter, Wolfgang, Weiss, Christian, Wullich, Bernd   +12 more
core  

Schistosomiasis and Urinary Bladder Cancer in North Western Tanzania: A Retrospective Review of 185 Patients. [PDF]

, 2013
Worldwide, cancers of the urinary bladder are well known to be associated with environmental chemical carcinogens such as smoking and occupational exposure to polycyclic aromatic hydrocarbons.
A Yosry, AH Zarzour, AJ Fulford, AS Felix, B Diao, CC Guo, CF Heyns, DMPP Parkin, DMWS Parkin, E Jacobo, H Abol-Enein, H Dietrich, HK Salem, I Gouda, IA Mungadi, JNLP Kitinya, JO Thomas, Kahima Jackson, KM Badr, M El-Sebaie, MJ Hess, MM Koraitim, MN El-Bolkainy, MS Zaghloul, NG El-Mawla, Peter Fabian Rambau, Philipo L Chalya, R Gonzalez Resina, RM Cooppan, RS Barsoum, SA Fedewa, SA Sheweita   +31 more
core   +1 more source

Trihalomethanes in Drinking Water and Bladder Cancer Burden in the European Union

Environmental Health Perspectives, 2020
Background: Trihalomethanes (THMs) are widespread disinfection by-products (DBPs) in drinking water, and long-term exposure has been consistently associated with increased bladder cancer risk.
Iro Evlampidou, Laia Font-Ribera, D. Rojas-Rueda, E. Gracia-Lavedán, N. Costet, N. Pearce, P. Vineis, J. Jaakkola, F. Delloye, K. Makris, E. Stephanou, S. Kargaki, F. Kožíšek, T. Sigsgaard, B. Hansen, J. Schullehner, Ramon Nahkur, C. Galey, C. Zwiener, M. Vargha, E. Righi, G. Aggazzotti, G. Kalnina, R. Gražulevičienė, K. Polańska, Dasa Gubkova, K. Bitenc, E. Goslan, M. Kogevinas, C. Villanueva   +29 more
semanticscholar   +1 more source