Results 91 to 100 of about 844,682 (297)

Voiding dysfunction - A review

open access: yesJournal of Indian Association of Pediatric Surgeons, 2005
In a child who is toilet trained the sudden onset of daytime wetting with frequency or urgency is alarming to the parents. Initially this subject was subdivided into a number of descriptive clinical conditions which led to a lot of confusion in ...
Sripathi V
doaj  

RETRACTED ARTICLE: Sulforaphane Improves Ischemia-Induced Detrusor Overactivity by Downregulating the Enhancement of Associated Endoplasmic Reticulum Stress, Autophagy, and Apoptosis in Rat Bladder

open access: yesScientific Reports, 2016
Atherosclerosis-associated pelvic ischemia has been reported to be a risk factor for bladder dysfunction and subsequent lower urinary tract symptoms (LUTS) in the elderly population.
Huai-Ching Tai   +3 more
doaj   +1 more source

Bladder, Bowel, and Sexual Dysfunction in Parkinson's Disease [PDF]

open access: yes, 2011
Bladder dysfunction (urinary urgency/frequency), bowel dysfunction (constipation), and sexual dysfunction (erectile dysfunction) (also called “pelvic organ” dysfunctions) are common nonmotor disorders in Parkinson's disease (PD).
Ryuji Sakakibara   +6 more
core   +1 more source

HADHA K406 Lactylation Regulates Metabolic Reprogramming and Suppresses Immune Responses in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
HADHA K406 lactylation fuels fatty acid β‐oxidation and HMGCR‐dependent cholesterol biosynthesis, fostering immunosuppressive MDSCs and exhausted CD8+ T cells in gastric cancer. Loss of this modification blocks cholesterol production, remodels the tumor microenvironment, and tumor growth is suppressed via combined inhibition of HMGCR and LDHA ...
Maoxiao Feng   +10 more
wiley   +1 more source

Photoactivated Platinum Complexes: Targeting Membrane Proteins and Organelles for Precision Cancer Therapy

open access: yesAngewandte Chemie, EarlyView.
This review highlights an emerging anticancer approach integrating platinum agents into photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) systems, further augmented by cancer cell membrane‐ and organelle‐targeting. By directing photoactivated platinum complexes from nontargeted distribution to cancer cells or defined subcellular sites ...
Shu Chen   +3 more
wiley   +2 more sources

Sacral Neural Crest‐Derived Extracellular Vesicles Promote Pelvic Ganglion Repair Through Anti‐Pyroptotic Effects Involving ANXA1–FPR2 Signaling

open access: yesAdvanced Science, EarlyView.
Extracellular vesicles derived from human pluripotent stem cell‐derived sacral neural crest cells promote repair of injured major pelvic ganglia and improve colorectal function. These vesicles reduce oxidative stress and pyroptosis, with ANXA1–FPR2 signaling contributing to their protective effects, and show a favorable therapeutic profile compared ...
Ting Yang   +11 more
wiley   +1 more source

Characteristics of Childhood Multiple Sclerosis

open access: yesPediatric Neurology Briefs, 1995
The clinical manfestations of multiple sclerosis (MS) in 14 children are reported from the Universidade de Sao Paulo, Brazil.
J Gordon Millichap
doaj   +1 more source

LncRNA FLJ20021 Restrains Fibroblast Senescence and Matrix Remodeling in Pelvic Organ Prolapse by Promoting XRCC6‐Dependent ADI1 Transcription

open access: yesAdvanced Science, EarlyView.
FLJ20021 interacts with XRCC6 to regulate ADI1 transcription and downstream cellular phenotypes in hUSLFs. Reduced FLJ20021 in POP is associated with lower ADI1, increased apoptosis, senescence, and an ECM‐degrading marker profile. Conversely, FLJ20021 overexpression enhances XRCC6‐dependent ADI1 expression, reduces apoptosis and senescence, and shifts
YanFeng Yang   +4 more
wiley   +1 more source

PRAZOSIN IN NEUROGENIC BLADDER DYSFUNCTION [PDF]

open access: yes, 1981
The clinical effect of Prazosin, an alpha blocking agent, was studied in 18 patients with neurogenic bladder dysfunction. The patients consisted of 11 supranuclear and 7 infranuclear type according to the neurological examinations. The daily doses of 0.5-
北村, 温   +8 more
core  

Diabetes series, 6. Diabetes and bladder dysfunction

open access: yes, 2017
Around half of all people with diabetes develop lower urinary tract symptoms (LUTS). The person with diabetes can develop an underactive or an overactive bladder ( Arrellano-Valdez et al, 2014 ).
Linda Nazarko
core   +1 more source

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