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A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci [PDF]
, 2010 We conducted a multi-stage, genome-wide association study of bladder cancer with a primary scan of 591,637 SNPs in 3,532 affected individuals (cases) and 5,120 controls of European descent from five studies followed by a replication strategy, which ...Taylor JA, Diver WR, Vermeulen, Sita H, Xifeng Wu, Allione A, Hildebrandt, MA, Hengstler JG, Besenbacher, S, Godfrey, A., Trichopoulos D, Tjonneland A, Teo MT, Nuria Malats, Koppova, Kvetoslava, Panico, S, Malcolm C Pike, Albanes, D, Prokunina-Olsson, L, Riboli, E., Baris, D, Yeager, M, Dietrich, H., Kiltie, Anne, Xu, Z, Kiemeney L, Benhamou, Simone, Allen, Naomi E, Vineis P, Fletcher T, Yuan J, Knowles, M.A., Silverman, DT, Taylor, JA, Alan Schned, Bishop, DT, Manolis Kogevinas, Mark T W Teo, Xu Z, Lloreta, J., Hutchinson A, Sanz-Velez JI, Colin P Dinney, Wheeler, William, Francisco X Real, Fletcher, T, Godfrey, Ashley, Valdivia G, Matullo, Giuseppe, Fraumeni, Joseph F, Klaus Golka, Cancel-Tassin, Geraldine, Czerniak, B., Stefansson, K, Peter Rudnai, Federico Canzian, Czerniak, Bogdan, Thun M, McGrath, Monica, Gago-Dominguez, M., Clavel-Chapelon, F, Sanchez, Manuel, Gago-Dominguez, M, Panico S, Sulem P, Chanock, Stephen J, McGrath M, Lloreta, Josep, 1958-, Mayordomo, Jose I, Dinney, Colin P, Vineis, Paolo, Ljungberg, Borje, Weinstein, SJ, Real, FX, Chatterjee N, Olivier Cussenot, H Bas Bueno-de-Mesquita, Kumar, Rajiv, Xu, Z., Tony Fletcher, Hushan Yang, Bueno-De-Mesquita, HB, Hildebrandt, M.A.T., Rothman N, Chen, Meng, Naomi E Allen, Jacobs EJ, Albanes, Demetrius, Karagas, MR, Margaret A Knowles, Mayordomo JI, Kiemeney LA, Dinney, CP, Gurzau, Eugen, Riboli, E, Riboli, Elio, Dinney CP, Chen M, Grubb R. 3rd, Baris, D., Consol Serra, Borje Ljungberg, Garcia-Closas, M., Hengstler, JG, Polidoro, S., Geraldine Cancel-Tassin, Cussenot, O, Caporaso, N., Pike, MC, Johnson, A, Real, F.X., Teo, MTW, McGrath, M., Sacerdote C, Kogevinas, M., Maria Teresa Landi, Landi, M.T., Canzian, F, Makkinje RR, Tardon, A., Johnson A, Caporaso, Neil, Stern, M.C., Cancel Tassin G, Jan G Hengstler, Caporaso N, Fulvio Ricceri, Vermeulen SH, Clavel-Chapelon, F., Lloreta J, Allen, NE, Koppova, K., Navarro, Carmen, Xu, ZL, Gapstur, SM, Schwenn, Molly, Karagas MR, Robert Grubb, Ljungberg, B, Allen NE, Sanz Velez JI, Serra, Consol, Godfrey, A, Polidoro, Silvia, Hunter, David J, María D García-Prats, Selinski, S., De Vivo, I., Prokunina Olsson L, Fu, YP, Virtamo, J., Schned, Alan, Alessandra Allione, José I Sanz-Velez, J Alfred Witjes, Garcia-Closas, R., Giuseppe Matullo, Teo, MT, Golka K, Adonina Tardón, Sanchez M, Chen, M., Van Den Berg, D, Chatterjee, N, Clavel Chapelon F, Bolick, S.C., Yang, H, Fu, Y., Mariana C Stern, Diver, W.R., Andriole, Gerald, Pike, Malcolm C, Rudnai, P, Yi-Ping Fu, Diver, W Ryan, Hunter, DJ, Grubb R 3rd, Margaret R Karagas, De Vivo, Immaculata, Kvetoslava Koppova, Besenbacher, S., Cortessis, Victoria K, Grubb R, Tjonneland, A., Stern, Mariana C, Carmen Navarro, Burdett, L., Anne Tjonneland, Andriole, G, Jacobs KB, Canzian, Federico, Fu Y, Elio Riboli, Laurie Burdett, Hengstler, Jan G, Serra, C, Karagas, Margaret R, De Vivo, I, Gapstur SM, Tardón García, Adonina, Czerniak B, Black, A, Wu, X, Baris, Dalsu, Guarrera, S, Eric J Jacobs, Teo, Mark T W, D García-Prats M, Eugen Gurzau, Taylor, Jack A, Yuan JM, Gago Dominguez M, Knowles MA, Golka, Klaus, Valdivia, Gabriel, Francoise Clavel-Chapelon, Guarrera, Simonetta, Michael Thun, Black A, García Closas R, Kiltie, Anne E, Fraumeni, JF, Benhamou, S, Lloreta, J, Besenbacher, Soren, Bolick, Sophia C E, McGrath, M, Ashley Godfrey, D García-Prats, María, Bolick, SCE, Kiltie, A.E., Kiltie AE, MA Hildebrandt, Dimitrios Trichopoulos, Cussenot, O., Wu, XF, Cancel-Tassin G, Rothman, Nathaniel, Hildebrandt MA, Rafnar, T, Trichopoulos, D., Brennan P, Virtamo J, Robert N Hoover, Purdue, Mark P, Grubb, R, Polidoro, S, Ricceri, F, Thun, M, Allen, N.E., Chanock, SJ, Allione, A., Yeager, Meredith, Thun, Michael, Porru S, Sanz-Velez, JI, Wu, X., Xu, Zongli, Jack A Taylor, Manuela Gago-Dominguez, Garcia-Closas, Montserrat, Debra T Silverman, Chatterjee, N., Monica McGrath, Koppova, K, Alison Johnson, Meng Chen, Makkinje, Remco R, Purdue, MP, Caporaso, N, Fraumeni JF Jr, Paul Brennan, Patrick Sulem, Chen, M, Brennan, P, Real FX, Trichopoulos, Dimitrios, Virtamo, Jarmo, Jacobs, E.J., Koppova K, Hildebrandt, MAT, De Vivo I, Allione, Alessandra, Purdue, M., Andriole G. Jr, Godfrey A, Brennan, Paul, Tjonneland, A, Schwenn, M, Vineis, P, Montserrat Garcia-Closas, Kiemeney, LA, Silverman, Debra T, Pike, M.C., Rajiv Kumar, Kevin B Jacobs, Schned, A., Sulem, P., Kiemeney, L.A.L.M., Sacerdote, C., Garcia Closas M, Canzian, F., Polidoro S, Zongli Xu, Hengstler, J.G., Jacobs, K.B., Baris D, Jacobs, EJ, Yang, HS, Wang, Z., Sophia C E Bolick, Black, A., Makkinje, R.R., García Closas, Montserrat, Trichopoulos, D, Katja K Aben, Berg, D.P.G. van den, Albanes, D., Jacobs, Eric J, Landi MT, Gurzau E, Kogevinas, M, Sacerdote, Carlotta, Porru, Stefano, Guarrera, S., Wang, Zhaoming, Rudnai P, Ljungberg, Börje,, Panico, Salvatore, Yang, H., Josep Lloreta, Hunter, D.J., Matullo G, Wheeler, W, Virtamo, J, Burdett, Laurie, Figueroa JD, Garcia-Prats, MD, Silverman DT, Tardón A, Jonine D Figueroa, Rafnar T, David J Hunter, Aben, K.K.H., Hoover, RN, Wang, Z, Wang, ZW, W Ryan Diver, Lloreta, Josep, Knowles, Margaret A, Wheeler, W., Prokunina-Olsson, L., D García-Prats, M, Landi, Maria Teresa, Kari Stefansson, Stephen J Chanock, Valdivia, G, Hildebrandt, Michelle AT, Bishop, David T, Joseph F Fraumeni, Figueroa, J.D., Garcia-Closas M, Ricceri, F., Immaculata De Vivo, Remco R Makkinje, Bueno de Mesquita HB, Malats, Nuria, Silvia Polidoro, Sulem, P, Pike MC, Cortessis, VK, Mayordomo, JI, Chanock, Stephen J., Mark P Purdue, Weinstein, Stephanie J, Thun, M., Hutchinson, A., Panico, S., Simone Benhamou, Chanock SJ, Bolick, SC, Bolick SC, Amanda Black, Tardon, A, Andriole G Jr, Dalsu Baris, Brennan, P., Allione, A, Hoover, Robert N, Fraumeni JF, Jian-Min Yuan, Meredith Yeager, Yeager, M., Karagas, M.R., Jose I Mayordomo, Landi, MT, Clavel-Chapelon F, Hunter DJ, Real, Francisco X, Matullo, G, Weinstein SJ, Soren Besenbacher, Hoover RN, Selinski, S, Hutchinson, A, Besenbacher S, Navarro C, Makkinje, RR, Cortessis, V.K., Rothman, N, Porru, S, Ludmila Prokunina-Olsson, Burdett, L, Andriole, G.L., Andriole G, Sacerdote, C, Malats, N., Figueroa, Jonine D, Sulem, Patrick, Prokunina-Olsson L, Anne E Kiltie, Ricceri F, Cussenot, Olivier, Stern, MC, Michelle A T Hildebrandt, Matullo, G., Johnson, A., Nilanjan Chatterjee, Kumar, R, CAPORASO, NICOLA, Tjonneland, Anne, Taylor, J.A., Kiltie, AE, Sita H Vermeulen, Demetrius Albanes, Real, Francisco X., William Wheeler, Gapstur, Susan M, Cortessis VK, Vilneis, P., Dietrich, Holger, Schwenn M, Jarmo Virtamo, Rafnar, Thorunn, Figueroa, JD, Vermeulen, SH, Bueno-de-Mesquita, H Bas, Guarrera S, Jacobs, Kevin B, Dietrich H, Cancel-Tassin, G, Dinney, C.P., Stefansson, Kari, Ricceri, Fulvio, Prokunina-Olsson, Ludmila, Serra, C., Chatterjee, Nilanjan, Grubb, R., Molly Schwenn, Vermeulen, S., Canzian F, García Prats MD, Cussenot O, Carlotta Sacerdote, Bolick, Sophia CE, Zhaoming Wang, Weinstein, S.J., Manuel Sanchez, Schwenn, M., Van Den Berg D, Hildebrandt, Michelle A T, Stern MC, Wheeler W, Clavel-Chapelon, Francoise, Rudnai, Peter, Malats N, Dietrich, H, Grubb, Robert, Bueno-De-Mesquita, H.B., Riboli E, Wu, Xifeng, Cancel-Tassin, G., Kogevinas M, Witjes, JA, Stefano Porru, Garcia-Closas, M, Gago-Dominguez M, Witjes, J Alfred, Purdue MP, Nathaniel Rothman, Simonetta Guarrera, Rafnar, T., Bishop, D.T., Garcia-Closas, R, Diver, WR, Albanes D, Fletcher, Tony, Gabriel Valdivia, Kiemeney, Lambertus A, Stefansson K, Susan M Gapstur, Aben, Katja K, Bishop DT, Yuan, JM, Victoria K Cortessis, Kogevinas, Manolis, Kumar R, Amy Hutchinson, Lambertus A Kiemeney, Bueno-de-Mesquita HB, Benhamou S, Yeager M, Witjes JA, Carrato, Alfredo, Gago-Dominguez, Manuela, Teo, M.T., Neil Caporaso, Wang Z, Ljungberg B, Wu X, Yang H, Gurzau, E, Yuan, Jian-Min, Schned, A, Serra C, Navarro, C, Reina García-Closas, Holger Dietrich, Golka, K., David T Bishop, Burdett L, Salvatore Panico, Aben, KK, Sanchez, M, Witjes, J.A., Yang, Hushan, D. García Prats M, Gapstur, S.M., Czerniak, B, Selinski, Silvia, Schned A, Silvia Selinski, Yuan, J.M., Stephanie J Weinstein, Sanz-Velez, José I, Carrato, A., Malats, N, Fu, Yi-Ping, Den Berg DV, Hutchinson, Amy, García-Closas R, Vivo ID, Knowles, MA, Thorunn Rafnar, Alfredo Carrato, Carrato, A, Johnson, Alison, Bogdan Czerniak, Gerald Andriole, Teo, Mark TW, Aben KK, Carrato A, Jacobs, KB, Mayordomo, J.I., Fletcher, T., Rudnai, P., Fu YP, Kumar, R., Paolo Vineis, Selinski S, Golka, K, David Van Den Berg, Black, Amanda, Jacobs, Eric J., Vermeulen, Sita H., Lloreta Trull, Josep, 1958-, Karagas, Margaret R., Mayordomo, Jose I., Kiltie, Anne E., Cortessis, Victoria K., Bishop, David T., Kiemeney, Lambertus A., Garcia-Closas, Reina, Stern, Mariana C., Hengstler, Jan G., Aben, Katja K., Makkinje, Remco R., Diver, W. Ryan, Witjes, J. Alfred, Silverman, Debra T., Figueroa, Jonine D., Bueno-de-Mesquita, H. Bas, Gapstur, Susan M., Sanz-Velez, Jose I., Bolick, Sophia C. E., Jacobs, Kevin B., Purdue, Mark P., Garcia-Prats, Maria D., Hunter, David J., Teo, Mark T. W., Weinstein, Stephanie J., Andriole, Gerald, Jr., Hildebrandt, Michelle A. T., Van den Berg, David, Allen, Naomi E., Taylor, Jack A., Dinney, Colin P., Fraumeni, Joseph F., Jr., Tardon, Adonina, Hoover, Robert N., Knowles, Margaret A., Grubb, Robert, III, Pike, Malcolm C. +611 morecore +2 more sourcesUCtracker: A Deep Learning–Based DNA Methylation Model for Noninvasive Diagnosis and Recurrence Surveillance of Urothelial Carcinoma in a Prospective Study
Advanced Science, EarlyView.We developed UCtracker, a urine DNA methylation–based deep learning model, for noninvasive diagnosis and postoperative surveillance of urothelial carcinoma. UCtracker demonstrates high diagnostic accuracy, robustness at ultralow sequencing depth, early recurrence detection, and dynamic risk‐stratified monitoring of molecular residual disease ...Shengwei Xiong, Gaojie Li, Yucai Wu, Yuan Liang, Heng Guo, Yu Zhang, Gengyan Xiong, Long Tian, Xin Zhang, Ye Tian, Zhengguo Ji, Bin Guo, Yue Shi, Jian Fan, Zhihua Li, Yanqing Gong, Shiming He, Xuesong Li, Weimin Ci, Liqun Zhou +19 morewiley +1 more sourceO‐GlcNAcylation Regulation of SNAP29‐Dependent Autophagy Activation Dictates Chemoresistance in Gastric Cancer
Advanced Science, EarlyView.Model illustrating the proposed mechanism by which chemotherapy‐induced downregulation of OGT disrupts SNAP29 O‐GlcNAcylation, promoting STX17‐SNAP29‐VAMP8 SNARE complex assembly and protective autophagy, leading to chemoresistance, which in turn establishes a feedforward loop to perpetuate drug tolerance.Liang Tang, Shaoji Zhao, Ziling Shao, Tao Luo, Baifu Peng, Yifan Liu, Jinning Ye, Jianjun Peng, Kaiyu Sun, Jianbo Xu +9 morewiley +1 more sourceA Clinicopathological Study of Urinary Bladder Neoplasms in Patients at Three Centers in Khartoum, Sudan [PDF]
, 2009 OBJECTIVES: To present the histopathological pattern of urinary bladder neoplasms using the WHO/ISUP classification system and relate it to the outcome.METHODS: This study was conducted in the period from January 2004 through December 2005 at three ...Dawi, N, A Shumo, N Husain, Mekki, S, Elsid, M, S Mekki, Shumo, A, N Dawi, M Elsid, Husain, N +9 morecore +1 more sourcePasta, a Versatile Transcriptomic Clock, Maps the Chemical and Genetic Determinants of Aging and Rejuvenation
Advanced Science, EarlyView.Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.Jérôme Salignon, Maria Tsiokou, Patricia Marqués, Enriqueta Rodríguez‐Diaz, Hazel Ang, Federico Pietrocola, Christian G. Riedel +6 morewiley +1 more sourceTherapeutic efficacy and short-term durability of trans-urethral amniotic bladder injections for the treatment of refractory COVID-associated cystitis
INTRODUCTION: COVID-19-associated cystitis (CAC) may arise following a COVID-19 infection and is characterized by the development of novel or worsening overactive bladder (OAB).O’Hollaren, Kyle, Considine, Jack A., Liaw, Aron, Dhar, Nivedita, O\u27Hollaren, Kyle, Considine, Jack A, Knapp, John, Radoiu, Codrut +7 morecore +1 more sourceEffects of curcumin in an orthotopic murine bladder tumor model
International Brazilian Journal of Urology, 2009 Cigarette smoking (CS) is the main risk factor for bladder cancer development. There are more than 100 carcinogens present in cigarette smoke. Among the potential mediators of CS-induced alterations is nuclear factor-kappa (NF-κB), which is ...Katia R. M. Leite, Daher C. Chade, Adriana Sanudo, Bruno Y. P. Sakiyama, Gustavo Batocchio, Miguel Srougi +5 moredoaj +1 more source
