Results 171 to 180 of about 64,876 (258)

Targeting lysine methyltransferase 2C deficiency: New frontiers in breast cancer therapy and prognosis

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
This graphical abstract illustrates the role of KMT2C loss‐of‐function in promoting breast cancer progression and therapeutic vulnerability. KMT2C deficiency drives tumor heterogeneity, metastasis, and therapy resistance by activating oncogenic pathways such as IFNγEMT/MET and MAPK/ERKRAS/PI3K/AKT/mTOR, along with epigenetic remodeling via the ...
Shuangmei Tong, Qiu Wang, Yun Chen, Zunjie Bo, Ya Zhang, Yan Liu   +5 more
wiley   +1 more source

‌CT image-derived radiomics predicts molecular subtypes in bladder urothelial carcinoma: validation of a non-invasive classification strategy. [PDF]

Sci Rep
Zhang Q, Guo Y, Lin F, Zuo Y, Jia X, Zhao J.   +5 more
europepmc   +1 more source

Anticancer Molecular Mechanisms of Curcuminoids: An Updated Review of Clinical Trials

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Curcuminoids remain one of the most studied dietary polyphenols as a cancer prevention and treatment agent. Inflammation and tumor progression are related to the NF‐κB signaling pathway, which is also suppressed by curcuminoids. Curcuminoids prevent the activation of a variety of signaling pathways, including the MAPK, PI3K/Akt, and NF‐kB pathways ...
Ushna Momal, Muhammad Shahbaz, Asfa Perween, Muhammad Hammad ul Hassan, Hammad Naeem, Zubda Shahid, Muzzamal Hussain, Muhammad Imran, Suliman A. Alsagaby, Waleed Al Abdulmonem, Mohamed A. Abdelgawad, Mohammed M. Ghoneim, Tadesse FentaYehuala, Samy Selim, Ehab M. Mostafa   +14 more
wiley   +1 more source

An interpretable machine learning model based on CT imaging for predicting lymphovascular invasion and survival in bladder urothelial carcinoma: a multicenter study. [PDF]

BMC Med Imaging
Xiao B, Zeng Q, Peng X, He Q, Xv Y, Wei Z, Xv Q, Lv F, Jiang Q, Wei S, Xiao M.   +10 more
europepmc   +1 more source

Loss of METTL3 m6A methyltransferase results in short‐term progression and poor treatment outcome of bladder cancer patients

International Journal of Cancer, Volume 158, Issue 3, Page 763-774, 1 February 2026.
What's new? Bladder cancer exhibits a highly heterogeneous molecular landscape and treatment response. The dysregulation of RNA modifications such as m6A has been involved in cancer initiation and progression. This study comprehensively analyzed the expression of the main catalytic component of the m6A methylation machinery in bladder tumors across one
Katerina‐Marina Pilala, Stella Koroneou, Maria‐Alexandra Papadimitriou, Konstantina Panoutsopoulou, Konstantinos Soureas, Georgios‐Christos Giagkos, Panagiotis Levis, Dimitrios Linardoutsos, Konstantinos Stravodimos, Margaritis Avgeris, Andreas Scorilas   +10 more
wiley   +1 more source

A Clinically Practical Nomogram for Predicting Survival in Elderly Patients (≥ 65 Years) With Bladder Urothelial Carcinoma: A Study Based on SEER Database and External Validation. [PDF]

Cancer Rep (Hoboken)
Wei J, Wei C, Chen J, Zhang X, Zhao W.
europepmc   +1 more source

Radiolabelled choline and FDG PET/CT: two alternatives for the assessment of lymph node metastases in patients with upper urinary tract urothelial carcinoma [PDF]

, 2015
Evangelista, Laura, Guttilla, Andrea, Zattoni, Fabio, Zattoni, Filiberto   +3 more
core   +1 more source

Unveiling a BRAF Signature Proficient in Accurately Capturing Oncogenic Activity and Guiding Prognostic Prediction Across Multiple Cancers

MedComm, Volume 7, Issue 2, February 2026.
The BRAF25 meta‐signature effectively captures BRAF‐driven oncogenic activity. By enabling precise patient stratification with distinct mutation profiles, BRAF25 identifies BRAF‐active tumor subtypes and provides superior prognostic value compared with mutation status alone.
Kaidi Yang, Shihui Fu, Jingbing Liang, Lijuan Ding, Junhao You, Fang Li, Ye Yuan, Xiu‐Wu Bian   +7 more
wiley   +1 more source

Analysis of the correlation between COL11A1 gene expression and clinical features in bladder urothelial carcinoma. [PDF]

Int J Clin Exp Pathol
Li J, Wang F, Wei X, Li P, Wang Q, Min H.   +5 more
europepmc   +1 more source

Noninvasive Early Detection and Recurrence Monitoring for Non‐Muscle‐Invasive Bladder Cancer via Urine Tumor DNA: A Prospective Clinical Study

MedComm, Volume 7, Issue 2, February 2026.
In NMIBC surveillance, positive postoperative utLIFE‐UC results before initial follow‐up cystoscopy were significantly associated with increased relapse risk. Longitudinal analysis showed that positive utLIFE‐UC results at any time after TURBT correlated with worse recurrence‐free survival, while sustained negative results predicted recurrence‐free ...
Junlong Wu, Shengming Jin, Qianming Bai, Huina Wang, Huanqing Cheng, Xiaoyan Zhou, Yijun Shen, Chunguang Ma, Chengyuan Gu, Hui Chen, Yafeng Zhang, Libin Chen, Shahrokh F. Shariat, Feng Lou, Shanbo Cao, Yiping Zhu, Dingwei Ye   +16 more
wiley   +1 more source