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Genomic and Phenotypic Analysis of bla KPC-2 Associated Carbapenem Resistance in Klebsiella aerogenes: Insights into Clonal Spread and Resistance Mechanisms Across Hospital Departments in Beijing. [PDF]
Jin H +11 more
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Genome sequencing unveils blaKPC-2-harboring plasmids as drivers of enhanced resistance and virulence in nosocomial Klebsiella pneumoniae. [PDF]
Han X +10 more
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Newly Detected Transmission of blaKPC-2 by Outer Membrane Vesicles in Klebsiella Pneumoniae
Current Medical Science, 2023The prevalence of carbapenem-resistant Klebsiella pneumoniae (CR-KP) is a global public health problem. It is mainly caused by the plasmid-carried carbapenemase gene. Outer membrane vesicles (OMVs) contain toxins and other factors involved in various biological processes, including β-lactamase and antibiotic-resistance genes. This study aimed to reveal
Liu-Jun, Chen +8 more
openaire +2 more sources
International Microbiology, 2021
Serratia marcescens has attracted increasing attention worldwide as a neglected opportunistic pathogen of public health concern, especially due to its antimicrobial resistance features, which usually cause nosocomial infections in immunocompromised or critically ill patients.In our study, four carbapenem-resistant Serratia marcescens (CRSM) clinical ...
Xiaokun, Wang +8 more
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Serratia marcescens has attracted increasing attention worldwide as a neglected opportunistic pathogen of public health concern, especially due to its antimicrobial resistance features, which usually cause nosocomial infections in immunocompromised or critically ill patients.In our study, four carbapenem-resistant Serratia marcescens (CRSM) clinical ...
Xiaokun, Wang +8 more
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Dissemination of blaKPC-2 in an NTEKPC by an IncX5 plasmid
Plasmid, 2019blaKPC-2 is disseminated worldwide usually in Tn4401, a Tn3-family transposon, and primarily in Klebsiella pneumoniae ST258, a well-known lineage that is distributed worldwide and responsible for several outbreaks. Although occurring rarely, blaKPC-2 has been described in non-Tn4401 elements (NTEKPCs), first in China and then in a few other countries ...
Rosineide Cardoso de, Souza +4 more
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Carbapenem Resistance via the blaKPC-2 Gene in Enterobacter cloacae Blood Culture Isolate
Southern Medical Journal, 2010An Enterobacter cloacae blood culture isolate expressing carbapenem resistance via the Klebsiella pneumoniae carbapenemase KPC-2 gene is reported. To our knowledge, this is the first report of a nosocomial isolate with carbapenemase-mediated resistance causing infection in a patient from Tennessee.
Andy, Lo +5 more
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Transplantation Proceedings, 2013
In renal transplant recipients, the urinary tract is the most common site of infections that might be caused by pathogens while on immunosuppressive therapy. The spread of enterobacteria resistant to carbapenem is worrying, as it is generally used as this agent is the first-line therapy for infections caused by Enterobacteriaceae producing extended ...
F, Cicora +4 more
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In renal transplant recipients, the urinary tract is the most common site of infections that might be caused by pathogens while on immunosuppressive therapy. The spread of enterobacteria resistant to carbapenem is worrying, as it is generally used as this agent is the first-line therapy for infections caused by Enterobacteriaceae producing extended ...
F, Cicora +4 more
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Science of The Total Environment, 2023
International high-risk clones of Klebsiella pneumoniae are important human pathogens that are spreading to the environment. In the COVID-19 pandemic scenario, the frequency of carbapenemase-producing strains increased, which can contribute to the contamination of the environment, impacting the surrounding and associated ecosystems. In this regard, KPC-
João Pedro Rueda, Furlan +6 more
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International high-risk clones of Klebsiella pneumoniae are important human pathogens that are spreading to the environment. In the COVID-19 pandemic scenario, the frequency of carbapenemase-producing strains increased, which can contribute to the contamination of the environment, impacting the surrounding and associated ecosystems. In this regard, KPC-
João Pedro Rueda, Furlan +6 more
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International Journal of Antimicrobial Agents, 2013
Univ Fed Pernambuco, Lab Resistencia Microbiana, Inst Ciencias Biol, BR-50100130 Recife, PE ...
Amanda Cristina, da Costa Guimarães +5 more
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Univ Fed Pernambuco, Lab Resistencia Microbiana, Inst Ciencias Biol, BR-50100130 Recife, PE ...
Amanda Cristina, da Costa Guimarães +5 more
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International Journal of Antimicrobial Agents
blaNDM-1 and blaKPC-2 are responsible for the global increase in carbapenem-resistant Klebsiella pneumoniae, posing a great challenge to public health. However, the impact of phylogenetic factors on the dissemination of blaNDM-1 and blaKPC-2 is not yet fully understood.
Yali, Zhang +6 more
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blaNDM-1 and blaKPC-2 are responsible for the global increase in carbapenem-resistant Klebsiella pneumoniae, posing a great challenge to public health. However, the impact of phylogenetic factors on the dissemination of blaNDM-1 and blaKPC-2 is not yet fully understood.
Yali, Zhang +6 more
openaire +2 more sources

