Results 141 to 150 of about 165,152 (266)

Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion

open access: yesAdvanced Science, EarlyView.
The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li   +10 more
wiley   +1 more source

A weather-forecast driven early warning system for wheat blast disease: User-centered design, validation, and scaling in Bangladesh and Brazil. [PDF]

open access: yesClim Serv
Krupnik TJ   +14 more
europepmc   +1 more source

Combination of Strobilurin and Triazole Chemicals for the Management of Blast Disease in Mushk Budji -Aromatic Rice. [PDF]

open access: yesJ Fungi (Basel), 2021
Mohiddin FA   +12 more
europepmc   +1 more source

ZMAT1 Promotes Osteoclastogenesis Through TRIM46 Mediated YAP1 Degradation and Inhibits Osteoblastogenesis

open access: yesAdvanced Science, EarlyView.
Zmat1 deficiency mitigates pathological bone loss by impairing osteoclastogenesis and promoting osteoblastogenesis. Mechanistically, in osteoclasts, Zmat1 loss relieves transcriptional repression of the E3 ligase TRIM46, promoting YAP1 degradation and inhibiting osteoclastogenic genes.
Xinyu Chang   +13 more
wiley   +1 more source

Importance of OsRac1 in Signalling of Pigm-1 Mediated Resistance to Rice Blast Disease. [PDF]

open access: yesPlants (Basel)
Yang D   +7 more
europepmc   +1 more source

Spatial distribution and identification of potential risk regions to rice blast disease in different rice ecosystems of Karnataka. [PDF]

open access: yesSci Rep, 2022
Amoghavarsha C   +12 more
europepmc   +1 more source

Extracellular Vesicles in Autoimmune Diseases: From Diagnostic Biomarkers to Engineered Therapeutics

open access: yesAdvanced Science, EarlyView.
This review provides a systematic comparison of extracellular vesicles (EVs) from both mammalian and plant sources in the context of autoimmune diseases. It highlights their emerging roles as precision biomarkers and engineered therapeutic platforms.
Yufei Wu   +6 more
wiley   +1 more source

Correction: Detection and characterization of fungus (Magnaporthe oryzae pathotype Triticum) causing wheat blast disease on rain-fed grown wheat (Triticum aestivum L.) in Zambia. [PDF]

open access: yesPLoS One
Tembo B   +11 more
europepmc   +1 more source

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