Results 131 to 140 of about 2,132,314 (341)

CsdA‐LaeB Regulatory Hub Contributes to Aspergillus fumigatus Virulence via Fumiquinazoline C Biosynthesis

Advanced Science, EarlyView.
This study identifies a conserved CsdA‐LaeB hub in Aspergillus fumigatus that regulates secondary metabolite fumiquinazoline C (FqC). Disrupting this hub enhances FqC production and virulence, shedding new light on the post‐transcriptional regulatory logic linking secondary metabolism to pathogenicity and offering alternative strategies for diagnostic ...
Zili Song, Hongjiao Zhang, Leixin Ye, Yuxin Lei, Linqi Wang, Xiao Liu, Nayanna M. Mercado Soto, Nancy P. Keller, Berl R. Oakley, Can Zhao, Michael Bromley, Hongwei Liu, Lei Cai, Koon Ho Wong, Wen‐Bing Yin   +14 more
wiley   +1 more source

Analysis of Otologic Injuries Due to Blast Trauma by Handmade Explosives

Turkish Archives of Otorhinolaryngology, 2017
Objective: The aim of this study is to identify the otologic injuries due to handmade explosive-welded blast travma in the law enforcement officers during the combat operations in the curfew security region and to specify the disorders that ...
Mustafa Aslıer, Nesibe Gül Yüksel Aslıer   +1 more
doaj   +1 more source

Accidental Blast Injuries While Making Indigenous Explosive Chemical Mixture: A Report of Two Incidents. [PDF]

Cureus, 2022
Jadav D, Bhowmik S, Saraf A, Gorchiya A, Meshram V, Shekhawat RS.   +5 more
europepmc   +1 more source

Reduction of epinephrine in the lumbar spinal cord following repetitive blast-induced traumatic brain injury in rats

, 2023
Shigeharu Tsuda, Golam Mustafa, Jiamei Hou, Kevin Wang, Floyd J. Thompson, Prodip Bose   +5 more
openalex   +1 more source

Single‐Cell Transcriptomic Atlases of Camels and Cattle Unravel Molecular Evolution of Digestive and Metabolic Systems

Advanced Science, EarlyView.
We generated multi‐tissue single‐cell transcriptomic atlases of camels and cattle, uncovering conserved and lineage‐specific cellular features across digestive and metabolic systems. Cross‐species comparisons revealed the evolutionary origin of the camel glandular sac and identified novel cell populations linked to physiological specialization ...
Tao Shi, Huiquan Shan, Haoping Wang, Xi Guo, Houcheng Li, Bo Han, Senlin Zhu, Fei Wang, Guanghui Tan, Zhannur Niyazbekova, Jilong Ren, Yaqi Zhou, Qi Zhang, Weijie Zheng, Minghui Jia, Ao Zhang, Xuesha Cao, Huizeng Sun, Dongxiao Sun, Lingzhao Fang, Yi Zheng, Xihong Wang, Yu Jiang   +22 more
wiley   +1 more source

Spectrum of neuromuscular injuries in victims of bomb blasts [PDF]

, 2015
Introduction: Bomb blast (BB) injuries outside war zones were a rare phenomenon until recently. With the spreading wave of terrorism across the globe, BB related trauma is resurfacing. Explosions can produce unique patterns of neuromuscular injury.
Iqrar, Ambreen, Kanwar, Dureshahwar, Khan, Sara, Shivji, Zaitoon   +3 more
core   +2 more sources

Selenoprotein H Functions as a PPARα Coactivator to Link Selenium Homeostasis to Hepatic Lipid Metabolism and Protect against Steatohepatitis

Advanced Science, EarlyView.
Our study identifies selenium deficiency as a hallmark of MASH pathogenesis. Dietary selenium supplementation enhances hepatic fatty acid oxidation (FAO) and attenuates MASH progression by activating the PPARα pathway via selenoprotein H (SELENOH). This selenium‐SELENOH‐PPARα nexus redefines the functional scope of selenoproteins, moving from redox ...
Yuwei Zhang, Yuchen Wang, Binbin Li, Xin Li, Chenyu Liu, Yanhao Chen, Cheng Tian, Dongmei Wang, Xiaosong Gu, Chunping Jiang, Yuda Wei, Qiurong Ding   +11 more
wiley   +1 more source

Hand grenade blast injuries in the Eastern Democratic Republic of Congo: a case series of 38 patients. [PDF]

BMC Emerg Med, 2022
Budema PM, Murhega RB, Tshimbombu TN, Toha GK, Cikomola FG, Mudekereza PS, Mubenga LE, Balemba GM, Badesire DC, Kanmounye US.   +9 more
europepmc   +1 more source

PIK3CA Mutations Downregulate PPT1 to Promote Adipogenesis by Suppressing P300 Depalmitoylation and Phase Separation

Advanced Science, EarlyView.
This study demonstrates that somatic PIK3CA mutations suppress PPT1 expression via activation of the PI3K–AKT–c‐JUN axis. This reduction in PPT1 weakens its interaction with P300, thereby increasing palmitoylation at C1176 of P300 and protecting P300 from lysosomal degradation.
Hongrui Chen, Zening Huang, Rui Chang, Wei Gao, Yajing Qiu, Bin Sun, Chen Hua, Xiaoxi Lin   +7 more
wiley   +1 more source

Links between traumatic brain injury and ballistic pressure waves originating in the thoracic cavity and extremities

, 2008
Identifying patients at risk of traumatic brain injury (TBI) is important because research suggests prophylactic treatments to reduce risk of long-term sequelae.
Alexander MP, Amy Courtney, Bruton C, Center for Disease Control and Prevention (CDC), Cernak I, Cernak I, Courtney M, Courtney M, Herrmann M, Krave U, Kushner DS, Kushner DS, Lowenstein DH, Margerison JH, Mayorga MA, Michael Courtney, Newgard K, Scott SG, Shaw NA, Stalnacke BM, Suneson A, Suneson A, Suneson A, Thompson HJ, Toth Z, Treib J, Trudeau DL, Vanderploeg RD, Vink R, Wang Q   +29 more
core   +1 more source