Results 221 to 230 of about 1,330,518 (288)

Integrated Blood Biomarker and Neurobehavioural Signatures of Latent Neuroinjury in Experienced Military Breachers Exposed to Repetitive Low-Intensity Blast. [PDF]

Int J Mol Sci
Di Battista AP, Shiu MY, Vartanian O, Tenn C, Nakashima A, Vallikanthan J, Lam T, Rhind SG.   +7 more
europepmc   +1 more source

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva, Caio Patrício de Souza Sena, Davi Serradella Vieira, Magdi E. A. Zaki, Leow Chiuan Yee, Shahina Akter, Umberto Laino Fulco, Jonas Ivan Nobre Oliveira, João Firmino Rodrigues‐Neto   +8 more
wiley   +1 more source

Fatigue Life Prediction of Pavement Base Layers Using Supersulfated Cement-Treated Aggregates Considering Stress-Dependent Resilient Modulus. [PDF]

Materials (Basel)
Deng J, Hu X, Li Y, Shan T, Zhang Y, Zhou Y.   +5 more
europepmc   +1 more source

Model‐informed optimal dose selection of golcadomide in combination with R‐CHOP in patients with previously untreated aggressive B‐cell lymphoma

British Journal of Clinical Pharmacology, EarlyView.
Aims Golcadomide is a potential first‐in‐class oral CELMoD™ agent for the treatment of lymphoma. This study aims to develop model‐informed drug development (MIDD) approaches to support optimal dose selection of golcadomide in combination with immunotherapy rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone (R‐CHOP) in alignment with ...
Xirong Zheng, Zhiling Yu, Mark Kaplan, Argyrios Gkasiamis, Akshay Sudhindra, Li Zhu, Manisha Lamba, Fan Wu   +7 more
wiley   +1 more source

Mechanical and Bond Performance of Alkali-Activated Slag Concrete Incorporating Natural and Recycled Diatoms. [PDF]

Materials (Basel)
Parra C, Belmonte IM, Calabuig Soler M, Benito F, Rodriguez C, Pacheco VM, Mateo JM, Carrión E, Torrano PH.   +8 more
europepmc   +1 more source

Combinatorial Metabolic Engineering of Alkane Biosynthesis in the Osmotolerant Yeast Debaryomyces hansenii CBS 767

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Debaryomyces hansenii is a yeast with diverse potential applications like producing oleochemicals from biomass. Yet, combinatorial metabolic engineering in D. hansenii is limited because, like many nonconventional organisms, key genomic data and genetic elements are missing. Here, we report phenotypic characterization, genomic integration loci,
Zekun Li, Nilesh Kumar Sharma, Sarah Weintraub, Eric Young   +3 more
wiley   +1 more source

Mechanistic Study on the Baseline Drift Phenomenon of Piezoelectric Pressure Sensors When Measuring Blast Waves. [PDF]

Sensors (Basel)
Li Y, Zhu J, Chen L, Cheng Q, Hui H, Li J, Yang J, Wu Z.   +7 more
europepmc   +1 more source

Whole‐Cell Production of Resolvin E2 and 17R‐Resolvin D5 by a Double‐Oxygenating 15S‐Lipoxygenase With 5S‐Lipoxygenase Activity From Pseudobdellovibrionaceae bacterium

Biotechnology and Bioengineering, EarlyView.
A recombinant whole‐cell platform expressing a bacterial 15S‐LOX exhibiting 5S‐LOX activity enabled the stereoselective production of RvE2 and 17R‐RvD5 from 18R‐HEPE and 17R‐HDHA, achieving final concentrations of 0.57 mM and 1.48 mM from 4.0 mM substrates, respectively, under optimized conditions.
Hee‐Gyeong Lee, Kyung‐Chul Shin, Deok‐Kun Oh   +2 more
wiley   +1 more source

Mechanical behavior of single concrete frame strengthened with externally prestressed cables. [PDF]

PLoS One
Gao X, Shang J, Song Y.
europepmc   +1 more source

Simulation of directional crack propagation by energy-absorbing blasting in deep gob-side entry retaining under different lateral pressure coefficients. [PDF]

PLoS One
Liu N, Guo C, Bao S, Wang T, Zhang F, Qin Z.   +5 more
europepmc   +1 more source