Results 71 to 80 of about 1,330,518 (288)

The Negative Phase of the Blast Load [PDF]

open access: yesInternational Journal of Protective Structures, 2014
Following the positive phase of a blast comes a period where the pressure falls below atmospheric pressure known as the negative phase. Whilst the positive phase of the blast is well understood, validation of the negative phase is rare in the literature, and as such it is often incorrectly treated or neglected altogether.
Rigby, S.   +4 more
openaire   +3 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Investigation of the Failure Response of Masonry Walls Subjected to Blast Loading Using Nonlinear Finite Element Analysis

open access: yesComputation, 2023
A numerical investigation of masonry walls subjected to blast loads is presented in this article. A non-linear finite element model is proposed to describe the structural response of the walls.
Sipho G. Thango   +2 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

ANLIK BASINÇ YÜKÜ ETKİSİ ALTINDAKİ KONSOL BİR PLAĞIN DİNAMİK ANALİZİ

open access: yesHavacılık ve Uzay Teknolojileri Dergisi, 2004
The response of elastic structures to time-dependent pulses, such as sonic boom and blast loadings, constitutes a subject that is currently of much interest in the design of aeronautical and space vehicles. The air-blast load, which is
Haydar Uyanık , Zafer Kazancı
doaj  

The interaction and pharmacological modulation of the cardiorespiratory responses to primary thoracic blast injury, haemorrhage resuscitation [PDF]

open access: yes, 2002
Blast injuries represent a problem for civilian and military populations. The response to thoracic blast injury involves a reflex bradycardia, hypotension and apnoea.
Sawdon, Mariana Annette   +2 more
core  

Effect of Blast Load on Soft Storey Building [PDF]

open access: yes, 2016
The number of terrorist activity have increased concern about safety of building. So, it’s became need to design building for blast load. This study compares the response of 3 dimensional soft storey building with Bare frame under blast loading.
, Patil Vijay.B, Bhilare .L.S, Patil .G.R
core   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

open access: yesFEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar   +11 more
wiley   +1 more source

Development of in-house high-resolution hydrocode for assessment of blast waves and its application

open access: yesZhongguo Jianchuan Yanjiu, 2017
The propagation and evolution characteristics of blast waves in confined spaces are complicated due to the constraint of the surrounding walls, by which the enhanced reflected shock waves will cause more serious damage to the internal structures ...
XU Weizheng, WU Weiguo
doaj   +1 more source

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