Results 81 to 90 of about 249,833 (291)

Study on wettability of water stemming for blasting dust adjusted by surfactants and inorganic salts

Royal Society Open Science
Water stemming is an efficient method of removing blasting dust by wetting. There is still a lack of methods for rapid optimization of water stemming components with high wettability. Herein, blasting dust was collected from a tunnel in Chongqing (China)
Fengjie Chen, Zejun Zhou, Ying Liang, Xiaowen Liu, Xiaoguang Wang, Pu Wang, Bolei Chen, Yong Liang, Yawei Wang   +8 more
doaj   +1 more source

Practical assessment of rock damage due to blasting

International Journal of Mining Science and Technology, 2019
Blasting is the most cost effective methodology to break rock for mining or civil engineering applications. A good production blast will break only the rock that is needed to be removed, leaving the host rock with minimal damage.
J. Silva, T. Worsey, B. Lusk
semanticscholar   +1 more source

Protein Language Model‐Guided Engineering of a 2,3‐Butanediol Dehydrogenase for the Enantioselective Synthesis of Cyclic α‐Hydroxy Ketones

Advanced Science, EarlyView.
A (2R,3R)‐butanediol dehydrogenase from Bacillus subtilis (BsBDH) is engineered for the enantioselective synthesis of 2‐hydroxycyclohexanone. A PASS computational design strategy is proposed to enhance the thermostability of BsBDH. Moreover, ESM‐1v combined with ISM is utilized for enhancing and inverting its stereoselectivity.
Haote Ding, Ling Jiang, Yijia Song, Zhongji Pu, Lirong Yang, Haoran Yu   +5 more
wiley   +1 more source

Study on iron based Fischer–Tropsch synthesis catalyst supported on mesoporous silica promoted by alkali and transition metals

Discover Chemical Engineering
Fischer Tropsch synthesis provides a non-petroleum pathway for the production of high value liquid fuels and long-chain alpha olefins from syngas. However, regulating product distribution to promote the formation of high value product while maintaining ...
Jun Wang, Zewan Bao, Peng Wang, Peiliang Feng, Quan Wang, Xuemei Shen, Luya Zhang, Yishuang Wang, Mingqiang Chen   +8 more
doaj   +1 more source

Instability mechanism of layered surrounding rock tunnels affected by layer thickness under dynamic and static loads

Alexandria Engineering Journal
In the context of the San Gavain hydroelectric power station diversion tunnel project in Peru, this paper studies the surrounding rock instability mechanism using a combination of numerical simulation methods and model test and presents the enclosing ...
Jianping Yao, Nan Jiang, Yingkang Yao, Chuanbo Zhou, Yumin Yang   +4 more
doaj   +1 more source

Modified scaled distance regression analysis approach for prediction of blast-induced ground vibration in multi-hole blasting

Journal of Rock Mechanics and Geotechnical Engineering, 2019
The blast-induced ground vibration prediction using scaled distance regression analysis is one of the most popular methods employed by engineers for many decades.
Hemant Agrawal, Ambuj Mishra
semanticscholar   +1 more source

Calcium Shock Enables Efficient and Programmable Particle Delivery for Genome Editing Applications

Advanced Science, EarlyView.
Classical transfection and transduction are inefficient, particularly with confluent cells and organoids, and lack cell type‐specific programmability. This study presents calcium shock (CaSh), a method that dramatically improves particle delivery into single cells, colonies, and organoids.
Nicole Vo, Lorena de Oñate, Maximillian Frank, Xian Hu, Sophie M. Blackburn, Dana V. Foss, Jasmine Villegas, Kunica Asija, Dirk Hockemeyer, Hongxia Fu, Raymond J. Monnat, Ross C. Wilson, Benjamin S. Freedman   +12 more
wiley   +1 more source

Experimental and numerical study on protective effect of RC blast wall against air shock wave

Defence Technology
Prototype experiments were carried out on the explosion-proof performance of the RC blast wall. The mass of TNT detonated in the experiments is 5 kg and 20 kg respectively. The shock wave overpressure was tested in different regions.
Xin-zhe Nian, Quan-min Xie, Xin-li Kong, Ying-kang Yao, Kui Huang   +4 more
doaj   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Comprehensive, experimental–simulative structure–property relation investigation of heterogeneous interface bonding by interlocks

Materials & Design
Precision manufacturing demands control over interfacial bonding properties, which relies on understanding the structure–property relationships. The authors applied experimental–simulative approach to investigate these relationships, specifically: a. RVE
Jiajin Li, Yidi Li, Guoqiang Luo, Ruizhi Zhang, Gang Yang, Jianian Hu   +5 more
doaj   +1 more source