Results 101 to 110 of about 89,734 (288)
Aging Cell, EarlyView.Autophagy regulates ovarian reserve, with Cathepsin B playing a critical role in aging. Inhibition of Cathepsin B increases follicle count, enhances IGF1R–AKT–mTOR signaling and improves mitochondrial function without compromising fertility. This conserved mechanism suggests potential therapeutic strategies to delay ovarian aging and sustain fertility,
Aradhana Mohanty +8 more
wiley +1 more source
Reproductive Medicine and Biology, 2019 Purpose To identify artificial intelligence (AI) classifiers in images of blastocysts to predict the probability of achieving a live birth in patients classified by age.
Yasunari Miyagi +3 more
doaj +1 more source
Human Reproduction, 2016 STUDY QUESTION Is blastocyst transfer safe when compared to cleavage stage embryo transfer regarding obstetric and perinatal outcomes? SUMMARY ANSWER The clinical equipoise between blastocyst and cleavage stage embryo transfer remains as the evidence ...
W. Martins +5 more
semanticscholar +1 more source
The Effect of Assisted Reproductive Technologies on Human Sex Ratios
Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.ABSTRACT Background Modern assisted reproductive technology (ART), including pre‐implantation genetic testing for aneuploidy (PGT‐A), has opened new avenues in understanding early embryonic events and has simultaneously raised questions about the impact of ART itself on sex ratios.
Ektoras X. Georgiou +6 more
wiley +1 more source
Reproductive Medicine and Biology, 2019 Purpose To identify the multivariate logistic regression in a combination (combination method) involving artificial intelligence (AI) classifiers in images of blastocysts along with a conventional embryo evaluation (CEE) to predict the probability of ...
Yasunari Miyagi +3 more
doaj +1 more source
Taiwanese Journal of Obstetrics & Gynecology, 2013 Objective: This study aimed to clarify the usefulness of blastocyst scores and female age as embryo competence markers for embryo transfer in in vitro fertilization (IVF) cycles. Materials and Methods: A total of 352 IVF cycles were investigated.
Tsung-Hsien Lee +6 more
doaj +1 more source
Andrology, EarlyView.Abstract Background Small RNAs interacting with PIWI (piRNAs) play a crucial role in regulating transposable elements and translation during spermatogenesis and are essential in male germ cell development. Disruptions in the piRNA pathway typically lead to severe spermatogenic defects and thus male infertility. The HENMT1 gene is a key player in piRNAs
Zeina Wehbe +17 more
wiley +1 more source
Andrology, EarlyView.Abstract Background Ascorbic acid 2‐glucoside (AA2G) is a stabilized form of ascorbic acid and a potent antioxidant. Ascorbic acid is present in the testes and epididymis and helps maintain the physiological integrity of reproductive organs. Its properties have been utilized to protect spermatozoa of different species from oxidative stress.
Marcello Raspa +2 more
wiley +1 more source
eLife, 2017 The number of children born since the origin of Assisted Reproductive Technologies (ART) exceeds 5 million. The majority seem healthy, but a higher frequency of defects has been reported among ART-conceived infants, suggesting an epigenetic cost.
Sebastian Canovas +9 more
doaj +1 more source
Andrology, EarlyView.Abstract Objective To examine the association between semen parameters, assessed according to World Health Organization (WHO)‐2021 criteria, and paternal body mass index (BMI) and age, with embryological and clinical outcomes in ICSI cycles involving preimplantation genetic testing for aneuploidy (PGT‐A).
Rossella Mazzilli +16 more
wiley +1 more source