Results 101 to 110 of about 133,185 (340)

Role of the Mitochondrial Genome During Early Development in Mice [PDF]

, 1973
The role of the mitochondrial genome in early development and differentiation was studied in mouse embryos cultured in vitro from the two to four cell stage to the blastocyst (about 100 cells).
Chase, David G., Pikó, Lajos
core  

A polyembryonic blastocyst in the opossum [PDF]

The Anatomical Record, 1917
n ...
Patterson, J. T., Hartman, C. G.
openaire   +3 more sources

Efficient Somatic Cell Nuclear Transfer by Overcoming Both Pre‐ and Post‐Implantation Epigenetic Barriers

Advanced Science, EarlyView.
Mammalian cloning via SCNT is limited by several epigenetic barriers. Kdm4d/Kdm5b overexpression plus TSA treatment overcomes epigenetic barriers during pre‐implantation development, while tetraploid complementation replaces defective extraembryonic lineages to bypass H3K27me3 imprinting loss to overcome epigenetic barriers in post‐implantation ...
Yamei Li, Shiyu Sun, Yuting Xu, Jixiang Zhang, Yi Du, Yaxin Cao, Zhaodi Liao, Yali Xie, Xinyan Bian, Jiantao Huang, Meijiao Wang, Zhen Liu, Qiang Sun, Falong Lu   +13 more
wiley   +1 more source

Nested Selves: Self‐Organization and Shared Markov Blankets in Prenatal Development in Humans

Topics in Cognitive Science, EarlyView., 2023
Abstract The immune system is a central component of organismic function in humans. This paper addresses self‐organization of biological systems in relation to—and nested within—other biological systems in pregnancy. Pregnancy constitutes a fundamental state for human embodiment and a key step in the evolution and conservation of our species. While not
Anna Ciaunica, Michael Levin, Fernando E. Rosas, Karl Friston   +3 more
wiley   +1 more source

Top quality blastocyst formation rates in relation to progesterone levels on the day of oocyte maturation in GnRH antagonist IVF/ICSI cycles

PLoS ONE, 2017
Cycles with progesterone elevation during controlled ovarian stimulation (COS) for IVF/ICSI are commonly managed with a “freeze-all” strategy, due to a well-recognized detrimental effect of high progesterone levels on endometrial receptivity.
V. S. Vanni, E. Somigliana, M. Reschini, L. Pagliardini, E. Marotta, S. Faulisi, A. Paffoni, P. Viganò, W. Vegetti, M. Candiani, E. Papaleo   +10 more
semanticscholar   +1 more source

Simulating the Mammalian Blastocyst - Molecular and Mechanical Interactions Pattern the Embryo [PDF]

, 2011
Mammalian embryogenesis is a dynamic process involving gene expression and mechanical forces between proliferating cells. The exact nature of these interactions, which determine the lineage patterning of the trophectoderm and endoderm tissues occurring ...
A Jedrusik, A Ralston, A Ralston, B Plusa, C Chazaud, Carsten Peterson, Denis Thieffry, E Palsson, F Graner, H Honda, H Niwa, H Niwa, J Rossant, JC Dallon, JE Dietrich, K Cockburn, K Piotrowska, K Piotrowska-Nitsche, K Piotrowska-Nitsche, M Bischoff, M Eyiyurekli, M Zernicka-Goetz, N Motosugi, N Nishioka, Pawel Krupinski, RA Foty, RL Gardner, SJ Kimber, SM Meilhac, T Fujimori, V Chickarmane, V Chickarmane, VB Alarcón, Vijay Chickarmane, Y Kurotaki, Y Marikawa, Y Yamanaka   +36 more
core   +5 more sources

FemXpress: Systematic Analysis of X Chromosome Inactivation Heterogeneity in Female Single‐Cell RNA‐Seq Samples

Advanced Science, EarlyView.
FemXpress is a computational tool that leverages X‐linked single nucleotide polymorphisms (SNPs) to group cells by the origin of the inactivated X chromosome in female single‐cell RNA sequencing (scRNA‐Seq) data. It demonstrates strong performance on both simulated and real datasets without requiring parental genomic information, and can also identify ...
Xin Wang, Yingke Ma, Fan Li, Wentao Cui, Tianshi Pan, Siqi Wang, Sinan Ma, Qingtong Shan, Chao Liu, Yukai Wang, Ying Zhang, Yuanchun Zhou, Wei Li, Pengfei Wang, Qi Zhou, Guihai Feng   +15 more
wiley   +1 more source

Large‐Scale Bioprinting of Human Epiblast‐Like Models Featuring Disc‐Shaped Morphogenesis and Gastrulation Events

Advanced Science, EarlyView.
Large‐scale generation of disc‐shaped models mimicking human epiblast layer is achieved by bioprinting of human pluripotent stem cells using a well‐defined biomatrix. The bioactive component and physical confinement from laminin/alginate microgels, combined with the endogenous regulation of the WNT signaling pathway regulated disc‐like morphogenesis ...
Yixue Luo, Liheng Luo, Ling Wang, Shanshan Yang, Hongan Ren, Shaojun Liang, Xiaoyu Wang, Yijun Su, Leqian Yu, Xiaoyue Wang, Mingen Xu, Rui Yao   +11 more
wiley   +1 more source

Uterine glands impact uterine receptivity, luminal fluid homeostasis and blastocyst implantation

Scientific Reports, 2016
Uterine glands are essential for pregnancy in mice and likely humans, because they secrete or transport bioactive substances that regulate uterine receptivity for blastocyst implantation.
A. M. Kelleher, G. Burns, S. Behura, Guoyao Wu, T. Spencer   +4 more
semanticscholar   +1 more source

The Critical Role of Enhanced OXPHOS and Mitochondrial Hyperpolarization in Simulated Microgravity‐Induced Oocyte Maturation Arrest

Advanced Science, EarlyView.
Simulated microgravity induces distinct mitochondrial hyperactivation patterns‐elevated OXPHOS and MMP‐which accelerate meiosis without SAC failure but delays MTOC coalescence, leading to spindle defects and meiotic arrest. Prolonging M‐phase restores MTOC assembly and oocyte maturation.
Lei Ge, Yuqing Gao, Feifei Du, Chiyuan Ma, Tianxia Xiao, Yali Yang, Xiaohua Lei, Jian V. Zhang   +7 more
wiley   +1 more source