Results 101 to 110 of about 147,588 (334)

Dad's Diet Shapes the Future: How Paternal Nutrition Impacts Placental Development and Childhood Metabolic Health

open access: yesMolecular Nutrition &Food Research, EarlyView.
This review highlights the emerging connection between paternal nutrition‐induced sperm epigenetic changes and placental phenotypes that may influence offspring metabolic health. An accompanying interactive ShinyApp allows exploration of these sperm–placenta gene networks, a framework for future research seeking to explore candidate biomarkers or ...
David A. Skerrett‐Byrne   +6 more
wiley   +1 more source

Harbingers of change: Towards a mechanistic understanding of anticipatory plasticity in animal systems

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Phenotypic plasticity is a strategy by which animals alter behaviour, morphology and/or physiology in response to cues of current conditions to cope with environmental heterogeneity.
Lauren Petrullo   +3 more
wiley   +1 more source

Embryo metabolism : what does it really mean? [PDF]

open access: yes, 2015
The study of early embryo metabolism has fascinated researchers in the field for nearly a century. Herein, we give a brief account of the general features of embryo metabolism and some consideration of the research performed to reach such conclusions. It
Lewis, Niamh, Sturmey, Roger
core  

Organ‐Specific Dedifferentiation and Epigenetic Remodeling in In Vivo Reprogramming

open access: yesAging Cell, EarlyView.
Transient in vivo expression of Yamanaka factors (OSKM) enhances regenerative competence and rejuvenation across multiple tissues. We highlight mechanistic links between injury‐induced dedifferentiation and OSKM reprogramming, while emphasizing safety challenges and the need for precise spatiotemporal control to enable clinical translation.
Beom‐Ki Jo   +4 more
wiley   +1 more source

Trophectoderm, Inner Cell Mass, and Expansion Status for Live Birth Prediction After Frozen Blastocyst Transfer: The Winner Is Trophectoderm

open access: yesLife
Despite advancements in technologies such as time-lapse microscopy and artificial intelligence, the gold standard for embryo selection still relies on standard morphological assessment. Several studies have investigated the correlation between blastocyst
Alessandro Bartolacci   +6 more
doaj   +1 more source

Feasibility of predicting live birth by combining conventional embryo evaluation with artificial intelligence applied to a blastocyst image in patients classified by age

open access: yesReproductive Medicine and Biology, 2019
Purpose To identify the multivariate logistic regression in a combination (combination method) involving artificial intelligence (AI) classifiers in images of blastocysts along with a conventional embryo evaluation (CEE) to predict the probability of ...
Yasunari Miyagi   +3 more
doaj   +1 more source

Histological cut of a paraffin-embedded blastocyst: Optimized protocol for murine blastocysts

open access: yesMethodsX, 2020
Paraffin-embedded tissues have been used for research and therapeutic applications for decades, as they represent a valuable tool in histology and for molecular analysis, as well as being a way to preserve tissue samples for long periods at a low cost.
José Mijares   +6 more
openaire   +4 more sources

The Effect of Assisted Reproductive Technologies on Human Sex Ratios

open access: yesAustralian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
ABSTRACT Background Modern assisted reproductive technology (ART), including pre‐implantation genetic testing for aneuploidy (PGT‐A), has opened new avenues in understanding early embryonic events and has simultaneously raised questions about the impact of ART itself on sex ratios.
Ektoras X. Georgiou   +6 more
wiley   +1 more source

POSSIBLILTIES FOR A SINGLE EMBRYO TRANSFER IN AN IN VITRO FERTILIZATION PROGRAMME

open access: yesZdravniški Vestnik, 2003
Background. Since in in vitro fertilization two embryos – blastocysts are routinely transferred, the twin pregnancy rates are higher than in the general population.
Irma Virant Klun   +12 more
doaj  

DNA methylation and gene expression changes derived from assisted reproductive technologies can be decreased by reproductive fluids

open access: yeseLife, 2017
The number of children born since the origin of Assisted Reproductive Technologies (ART) exceeds 5 million. The majority seem healthy, but a higher frequency of defects has been reported among ART-conceived infants, suggesting an epigenetic cost.
Sebastian Canovas   +9 more
doaj   +1 more source

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