Results 111 to 120 of about 56,325 (220)
ABSTRACT While molecular signature contributes to sperm quality and fertility potential, sperm may lost key molecules during cryopreservation. Since sperm cells are transcriptionally inert and rely on interactions with epididymosomes (epEVs) to acquire molecules, herein, we investigated the effects of the addition of epEVs to the cryopreservation ...
Laura Gabrielli Haupenthal +9 more
wiley +1 more source
Follicle size modulates bovine oocyte cytoplasmic maturation during IVM. Oocytes from larger follicles exhibit reduced lipid accumulation, fewer transzonal projections, distinct cumulus cell metabolic signaling, and greater embryo cryosurvival, indicating improved cytoplasmic maturation and lipid regulation despite similar developmental rates ...
Briza Castro +2 more
wiley +1 more source
ASK1‐Induced FGF21 Synthesis in the Liver Prevents Obesity in Mice
ABSTRACT Objective Fibroblast growth factor 21 (FGF21) is a stress‐induced hormone secreted by the liver. It has a beneficial role in the regulation of glucose and energy metabolism. Herein, we identify apoptosis signal regulating kinase 1 (ASK1) as an inducer of hepatic FGF21 synthesis.
Anne Goergen +8 more
wiley +1 more source
In this work, we develop submicron‐resolution mapping of intracellular lipid elements (SMILE) as an extraction‐free vibrational spectroscopic imaging platform based on hyperspectral stimulated Raman scattering microscopy with a spectral analysis pipeline for pixel‐resolved lipid profiling.
Yihui Zhou +10 more
wiley +1 more source
Objective To clarify the impact of chromosomal aberrations on the offspring of patients with testicular germ cell tumour (TGCT) by evaluating the outcomes of intracytoplasmic sperm injection (ICSI). Patients and Methods Under the ethical review of Yokohama City University, 12 patients with TGCT and 25 with non‐TGCT cancer who had cryopreserved sperm ...
Haru Hamada +21 more
wiley +1 more source
Overcoming Batch Variability: A Chemically Defined XRS-Based System for Ovine In Vitro Embryo Production. [PDF]
Wang Y +9 more
europepmc +1 more source
The hfPSC‐LCs could be established from naïve hESCs, conventional hESCs, hiPSCs, and human blastocysts. The hfPSC‐LCs hold robust capacity for three germ layers, hPGCLCs, and hALPCs. ABSTRACT Human embryos undergo pivotal morphogenetic remodelling shortly after implantation. The understanding of this crucial stage is severely impeded by the scarcity of
Xiaoxiao Wang +11 more
wiley +1 more source
ABSTRACT The aim of this study was to evaluate the effect of anethole addition to the ovine oocyte in vitro maturation (IVM) medium on viability and chromatin configuration, intracellular production of reactive oxygen species (ROS), enzymatic activity of superoxide dismutase (SOD) and catalase (CAT), as well as the levels of reduced thiols in IVM ...
Anderson Nascimento de Andrade +10 more
wiley +1 more source
Vitrification with shortened equilibration across human embryonic developmental stages: a proof-of-concept study. [PDF]
Doolman N +6 more
europepmc +1 more source
Maternal age and blastocyst morphology as independent predictors of embryonic euploidy in preimplantation genetic testing cycles: A retrospective cohort study. [PDF]
Huang H +5 more
europepmc +1 more source

