Results 21 to 30 of about 258 (79)
Detection of Blastomyces gilchristii via metagenomic sequencing in outbreak-associated soils
Abstract Cases of blastomycosis, a serious fungal disease globally rare but endemic to North America, can appear both sporadically and in outbreaks. Tracing these outbreaks to their environment has traditionally used culturing and polymerase chain reaction.
Alexandra M Linz +2 more
openaire +2 more sources
Genomic Epidemiology of Large Blastomycosis Outbreak, Ontario, Canada, 2021
Using phylogenomic analysis, we provide genomic epidemiology analysis of a large blastomycosis outbreak in Ontario, Canada, caused by Blastomyces gilchristii.
Lisa R. McTaggart +4 more
doaj +1 more source
Crosstalk Between Intratumoral Microbes and Tumor Immunity: Implications for Tumor Therapy
ABSTRACT Background Emerging studies indicate that microbes are present in tumor cells and immune cells. Intratumoral microbiota (ITM) constitute an important component of the tumor immune microenvironment (TIME) and have an important impact on tumor progression and treatment. Objective Through the general elaboration of ITM represented by bacteria and
Fengxue Li +13 more
wiley +1 more source
Reactive oxygen species induce mutagenic DNA lesions, such as 8‐oxo‐2′‐deoxyguanosine (8‐oxodG), which acts as a template for dCMP and dAMP incorporation through its anti and syn conformations. Specific residues must regulate the fidelity of templated 8‐oxodG.
Noe Baruch‐Torres +10 more
wiley +1 more source
Benign and malignant cutaneous nasal lesions
Abstract The nose is a structure of both cosmetic and functional importance. Cutaneous lesions of the nose occasionally represent a diagnostic challenge and involve the expertise of several specialties from dermatology, otolaryngology—head and neck surgery, infectious disease, and pathology, among others.
Hamed Sarikhani +4 more
wiley +1 more source
ABSTRACT Background Blastomycosis is a pulmonary disease caused by Blastomyces spp., a group of pathogenic dimorphic fungi endemic to a number of geographic regions, specifically Manitoba and northwestern Ontario, Canada. Immunosuppression is a major risk factor affecting disease susceptibility, yet host immunity is not well understood.
Paul Jankowski +4 more
wiley +1 more source
“Nutrient–fungi–host” tripartite interaction in cancer progression
Interactions between nutrient and fungi in cancer development and treatment remain under investigation. In this article, we aim to provide insights into the relationships between fungi and various categories of cancer, mediated by diverse nutrient sensing pathways of fungi in response to external environment.
Di Wu +6 more
wiley +1 more source
Endemic Mycoses on the African Continent
The review of the current microbiological, epidemiological and diagnostic aspects of some endemic mycoses (histoplasmosis, blastomycosis, emergomycosis) found on the African continent is brought forward.
A. V. Lipnitsky +9 more
doaj +1 more source
Host–microbiota interaction during cancer progression from bulk to single‐cell level
Host–microbiota interactions play a critical role in cancer progression from bulk to single‐cell level. Growing technologies focus on characterizing the host–microbiota interaction. Microbiota‐derived metabolites and components and themselves affect the host immune response and the proliferation of cancer cells. Microbiota is emerging as the target for
Yong‐Jing Ma +2 more
wiley +1 more source

