Results 31 to 40 of about 2,676 (105)

Fungal Dimorphism and Virulence: Molecular Mechanisms for Temperature Adaptation, Immune Evasion, and In Vivo Survival

Mediators of Inflammation, Volume 2017, Issue 1, 2017., 2017
The thermally dimorphic fungi are a unique group of fungi within the Ascomycota phylum that respond to shifts in temperature by converting between hyphae (22–25°C) and yeast (37°C). This morphologic switch, known as the phase transition, defines the biology and lifestyle of these fungi.
Gregory M. Gauthier, Anamélia L. Bocca
wiley   +1 more source

Detection of Histoplasma capsulatum and Blastomyces dermatitidis antigens in serum using a single quantitative enzyme immunoassay

Journal of Clinical Microbiology, 2023
Histoplasma and Blastomyces antigen detection assays are commonly used diagnostic tools. However, a high level of cross-reactivity between these antigens prevents definitive pathogen identification by these assays alone.
D. Granger, Nicholas T. Streck, E. Theel
semanticscholar   +1 more source

Blastomyces dermatitidis Septic Arthritis in a Renal Transplant Patient

Journal of Investigative Medicine High Impact Case Reports, 2023
Blastomycosis is a rare endemic fungal infection caused by the dimorphic fungus Blastomyces dermatitidis. It is more likely to occur in persons living in areas of the United States and Canada, which border the Ohio and Mississippi River Valleys and the ...
Stacy Ploom, M. Cooley, A. Nagpal, D. Guerrero   +3 more
semanticscholar   +1 more source

CsdA‐LaeB Regulatory Hub Contributes to Aspergillus fumigatus Virulence via Fumiquinazoline C Biosynthesis

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This study identifies a conserved CsdA‐LaeB hub in Aspergillus fumigatus that regulates secondary metabolite fumiquinazoline C (FqC). Disrupting this hub enhances FqC production and virulence, shedding new light on the post‐transcriptional regulatory logic linking secondary metabolism to pathogenicity and offering alternative strategies for diagnostic ...
Zili Song, Hongjiao Zhang, Leixin Ye, Yuxin Lei, Linqi Wang, Xiao Liu, Nayanna M. Mercado Soto, Nancy P. Keller, Berl R. Oakley, Can Zhao, Michael Bromley, Hongwei Liu, Lei Cai, Koon Ho Wong, Wen‐Bing Yin   +14 more
wiley   +1 more source

A Case of Blastomyces dermatitidis Diagnosed Following Travel to Colorado: A Case Report and Review of Literature

Cureus, 2023
The dimorphic fungus Blastomyces dermatitidis, is one of the most frequent causes of endemic fungal infections in the United States as well as various other parts of the world. Clinical presentations vary widely, ranging from asymptomatic to disseminated
Gaurav Venkat Cuddapah, Mayra Z Malik, Amulya Arremsetty, Andrew Fagelman   +3 more
semanticscholar   +1 more source

Crosstalk Between Intratumoral Microbes and Tumor Immunity: Implications for Tumor Therapy

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Emerging studies indicate that microbes are present in tumor cells and immune cells. Intratumoral microbiota (ITM) constitute an important component of the tumor immune microenvironment (TIME) and have an important impact on tumor progression and treatment. Objective Through the general elaboration of ITM represented by bacteria and
Fengxue Li, Lili Qiao, Xinquan Liang, Yingying Zhang, Ning Liang, Jian Xie, Guodong Deng, Yuying Hao, Pingping Hu, Xue Wu, Fangjie Ding, Can Feng, Yiming Mu, Jiandong Zhang   +13 more
wiley   +1 more source

Clinical manifestations and treatment of blastomycosis

Clinics in Chest Medicine, 2017
Synopsis The etiologic agents of blastomycosis, Blastomyces dermatitidis and B. gilchristii, belong to a group of thermally dimorphic fungi that can infect healthy and immunocompromised individuals.
Joseph A. McBride, G. Gauthier, B. Klein
semanticscholar   +1 more source

Persistent and nonprogressive cutaneous blastomycosis in a pregnant adolescent

JAAD Case Reports, 2020
Blastomycosis is a fungal infection endemic to the Great Lakes region and Mississippi River Valley,1 although it is found worldwide. Although asymptomatic infections have been recognized, blastomycosis is usually a respiratory syndrome with rare cases of
Jennifer L. Anderson, Matthew C. Hall, E. Stratman, J. Meece   +3 more
semanticscholar   +1 more source

In vitro manogepix susceptibility testing of South African Emergomyces africanus, Emergomyces pasteurianus, and Blastomyces emzantsi clinical isolates

Antimicrobial Agents and Chemotherapy, 2023
We performed in vitro antifungal susceptibility testing of manogepix against the yeast phase of 78 Emergomyces africanus, 2 Emergomyces pasteurianus, and 5 Blastomyces emzantsi isolates using a reference broth microdilution method following Clinical and ...
Silondiwe Nzimande, N. Govender, Tsidiso G. Maphanga   +2 more
semanticscholar   +1 more source

In silico-based identification of some selected phytoconstituents in Ageratum conyzoides Leaves as potential inhibitors of crucial proteins of Blastomyces dermatitidis

Biomedical and Biotechnology Research Journal (BBRJ), 2022
Background: Blastomyces dermatitidis poses health threats to humans due to the frequency of infections (blastomycosis) and the increasing resistance to existing standard antifungal drugs.
M. Sakyiamah, Evans Larbi, S. Kwofie
semanticscholar   +1 more source