Results 41 to 50 of about 2,676 (105)

A steric gate prevents mutagenic dATP incorporation opposite 8‐oxo‐deoxyguanosine in mitochondrial DNA polymerases

The FEBS Journal, Volume 292, Issue 13, Page 3430-3448, July 2025.
Reactive oxygen species induce mutagenic DNA lesions, such as 8‐oxo‐2′‐deoxyguanosine (8‐oxodG), which acts as a template for dCMP and dAMP incorporation through its anti and syn conformations. Specific residues must regulate the fidelity of templated 8‐oxodG.
Noe Baruch‐Torres, Carlos H. Trasviña‐Arenas, Alexandru Ionut Gilea, Upeksha C. Dissanayake, Missael Molina‐Jiménez, Paola L. García‐Medel, Corina Díaz‐Quezada, Tiziana Lodi, G. Andrés Cisneros, Enrico Baruffini, Luis G. Brieba   +10 more
wiley   +1 more source

Benign and malignant cutaneous nasal lesions

Eye &ENT Research, Volume 1, Issue 2, Page 65-91, December 2024.
Abstract The nose is a structure of both cosmetic and functional importance. Cutaneous lesions of the nose occasionally represent a diagnostic challenge and involve the expertise of several specialties from dermatology, otolaryngology—head and neck surgery, infectious disease, and pathology, among others.
Hamed Sarikhani, Karena Zhao, Marc A. Polacco, Charles Gropper, Samuel N. Helman   +4 more
wiley   +1 more source

Exome Sequencing of a Blastomycosis Case–Control Cohort From Manitoba and Northwestern Ontario, Canada

Mycoses, Volume 67, Issue 9, September 2024.
ABSTRACT Background Blastomycosis is a pulmonary disease caused by Blastomyces spp., a group of pathogenic dimorphic fungi endemic to a number of geographic regions, specifically Manitoba and northwestern Ontario, Canada. Immunosuppression is a major risk factor affecting disease susceptibility, yet host immunity is not well understood.
Paul Jankowski, Emma R. Lee, John Embil, Yoav Keynan, Paul J. McLaren   +4 more
wiley   +1 more source

“Nutrient–fungi–host” tripartite interaction in cancer progression

iMeta, Volume 3, Issue 2, April 2024.
Interactions between nutrient and fungi in cancer development and treatment remain under investigation. In this article, we aim to provide insights into the relationships between fungi and various categories of cancer, mediated by diverse nutrient sensing pathways of fungi in response to external environment.
Di Wu, Yun‐Xuan Guan, Chen‐Hao Li, Quan Zheng, Zuo‐Jing Yin, Hui Wang, Ning‐Ning Liu   +6 more
wiley   +1 more source

Host–microbiota interaction during cancer progression from bulk to single‐cell level

Clinical and Translational Discovery, Volume 4, Issue 1, February 2024.
Host–microbiota interactions play a critical role in cancer progression from bulk to single‐cell level. Growing technologies focus on characterizing the host–microbiota interaction. Microbiota‐derived metabolites and components and themselves affect the host immune response and the proliferation of cancer cells. Microbiota is emerging as the target for
Yong‐Jing Ma, Run‐Ze Zhu, Ning‐Ning Liu   +2 more
wiley   +1 more source

Cutaneous, Intranasal Blastomycosis Infection in Two Patients from Southern West Virginia: Diagnostic Dilemma

Cureus, 2018
Blastomycosis is a dimorphic fungus caused by the species of Blastomyces dermatitidisand Blastomyces gilchristii, which are endemic to the Ohio River and Mississippi River Valleys. It is commonly found in soil or decomposing wood.
Aaron R Kuzel, M. Lodhi, Intekhab Askari Syed, Tehmina Zafar, Umar Rahim, Mehenaz Hanbazazh, N. Naumova, Mustafa Rahim   +7 more
semanticscholar   +1 more source

Retrospective analysis of the effects of Blastomyces antigen concentration in urine and radiographic findings on survival in dogs with blastomycosis

Journal of Veterinary Internal Medicine, 2021
Background The Blastomyces antigen concentration in urine (BACU) test is used to diagnose blastomycosis and monitor treatment in dogs. It is unknown if a higher BACU is associated with shorter survival.
L. Motschenbacher, E. Furrow, A. Rendahl, Esther Nell, K. Anderson, L. Merkel, E. Patterson   +6 more
semanticscholar   +1 more source

Closing the Brief Case: Laryngeal Blastomycosis Involving a Vocal Cord Implant

Journal of Clinical Microbiology, 2019
1. Blastomyces dermatitidis/gilchristii has a geographic area of endemicity that largely overlaps which other thermally dimorphic fungus? Answer: b. Blastomyces dermatitidis’s geographic area of endemicity spans the Ohio and Mississippi River valleys ...
Alexander J. Fenwick, Noah D McKittrick, Sean X. Zhang   +2 more
semanticscholar   +1 more source

Blastomycosis: An Underrecognized Climate Sensitive Fungal Pathogen Causing Pneumonia in 52-year-old Immunocompetent Women from Southwestern Ohio—A Case Report and Literature Review

Archives of medical case reports
Blastomycosis, formerly known as Gilchrist disease, Chicago disease, North American blastomycosis, or Namekagos fever, is an uncommon but underappreciated fungal infection seen mostly in immunocompetent people, caused by the fungi Blastomyces ...
Danny Sameh Darwich, Wissam Sabbagh, Bana Alajati   +2 more
semanticscholar   +1 more source

Phylogeny, ecology and taxonomy of systemic pathogens and their relatives in Ajellomycetaceae (Onygenales): Blastomyces, Emergomyces, Emmonsia, Emmonsiellopsis

Fungal diversity, 2018
The family Ajellomycetaceae (Onygenales) includes mammal-associated pathogens within the genera Blastomyces, Emmonsia, Histoplasma and Paracoccidioides, as well as the recently described genera, Emergomyces that causes disease in immunocompromised hosts,
Yan-Ping Jiang, K. Dukik, J. Muñoz, L. Sigler, Ilan S. Schwartz, N. Govender, C. Kenyon, P. Feng, B. G. van den Ende, J. B. Stielow, A. Stchigel, Hong-Guang Lu, S. de Hoog   +12 more
semanticscholar   +1 more source