Results 31 to 40 of about 14,606,477 (205)

Preliminary phytochemical analysis and hemostatic activity of the ethanolic leaf extract of Vernonanthura tweedieana (Baker) H.Rob. in mice

Vitae
BACKGROUND: Currently available hemostatic agents have important limitations, including high cost, adverse effects, and limited accessibility. Vernonanthura tweedieana (Baker) H.Rob.
Wilfrido J. Arrúa, Antonia K. Galeano, Olga Y. Heinichen, Andrea Cáceres, Juan R. Centurión, Rosa Degen, María Del Carmen Hellión Ibarrola, Derlis A. Ibarrola   +7 more
doaj   +1 more source

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad, Ohad Atia, Osama Tanous, Dafna Brik Simon, Michal Dvori, Miriam Cohen, Tracie A. Goldberg, Efraim Bilavsky, Joanne Yacobovich, Orna Steinberg‐Shemer   +9 more
wiley   +1 more source

Classical Complement Pathway Inhibition in a Pediatric Patient With Refractory Immune Thrombocytopenia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh, Susmita Sarangi, Caileigh Pudela, Catherine M. Broome, Tara K. Suntum   +4 more
wiley   +1 more source

ASSOCIATION OF THROMBOCYTOPENIA AND PROLONGED BLEEDING TIME IN DENGUE WITH THE CLINICAL OUTCOME OF THE PATIENT

Pakistan Armed Forces Medical Journal, 2019
Objective: To find out the frequency of thrombocytopenia and prolonged bleeding time in dengue fever and its effect on clinical outcome of patients. Study Design: Cross-sectional study.
Zareen Irshad, Asma Shabbir, Asma Shaikh, Syed Mehmood Hasan, Muhammad Abid   +4 more
doaj  

Thus far there are no statistically significant differences between various apolipoprotein E genotypes in the cluster of seven responsiveness to a flaxseed oil supplement in persons with type 2 diabetes

Endocrine Regulations
Objective. The objective of the present study was to determine if there would be statistically significant differences among apolipoprotein E genotypes in the responsiveness of members of a cluster of seven measures in persons with type 2 diabetes ...
Barre Douglas E., Mizier-Barre Kazimiera A., Griscti Odette   +2 more
doaj   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Synthesis and Preliminary Evaluation of N-Oxide Derivatives for the Prevention of Atherothrombotic Events

Molecules, 2015
Thrombosis is the main outcome of many cardiovascular diseases. Current treatments to prevent thrombotic events involve the long-term use of antiplatelet drugs.
Leandro Augusto Rosseto, Maria Elisa Lopes Pires, Aylime Castanho Bolognesi Melchior, Priscila Longhin Bosquesi, Aline Renata Pavan, Sisi Marcondes, Man Chin Chung, Jean Leandro dos Santos   +7 more
doaj   +1 more source

Effect of ketorolac, ketoprofen and nefopam on platelet function

, 1994
Ketorolac, ketoprofen and nefopam are often used in the treatment of postoperative pain. While nefopam is a non-narcotic, non-opioid central analgesic agent, ketorolac and ketoprofen are non-steroidal anti-inflammatory drugs, which, due to their ...
A. STEFANELLI, P. PAPARELLA, M. DELLA VENTURA, E. IANNACE, P. L. DORDONI, F. ACCORRA, Rocca, Bianca, B. ROCCA   +7 more
core   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source