Results 1 to 10 of about 31,566,991 (117)
Brazilian Journal of Medical and Biological Research, 2003 Studies that consider polymorphisms within the apolipoprotein B (apo B) gene as risk factors for coronary artery disease (CAD) have reported conflicting results.
Antonio Pazin-Filho +2 more
exaly +3 more sources
NAFLD‐related hepatocellular carcinoma: The growing challenge
Hepatology, EarlyView., 2022 Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah +2 more
wiley +1 more source
Association of ApoE gene polymorphisms with serum lipid levels and the risk of type 2 diabetes mellitus in the Chinese Han population of central China [PDF]
PeerJ, 2023 Background Apolipoprotein E (ApoE) is involved in lipid transformation and metabolism. Although some studies have examined the association between ApoE polymorphisms and the risk of type 2 diabetes mellitus (T2DM), the findings differ depending on the ...
Yali Zeng +5 more
doaj +2 more sources
International Journal of Hypertension, 2022 Objective. One of the causes of hypertension is a genetic factor. The purpose of this study was to look at the relationship between apolipoprotein E (APOE) and methylenetetrahydrofolate reductase (MTHFR) polymorphisms and essential hypertension in the ...
Hui Rao +3 more
doaj +1 more source
Lipids in Health and Disease, 2020 Background Apolipoprotein E (ApoE) and solute carrier organic anion transporter family member 1B1 (SLCO1B1) regulate lipid metabolism. However, the relationship between genetic polymorphisms of APOE and SLCO1B1 and cerebral infarction (CI) remains ...
Heming Wu +4 more
doaj +1 more source
Journal of Diabetes Research, 2021 Background. The apolipoprotein E (APOE) gene polymorphisms have been intensively studied in patients with type 2 diabetes mellitus (T2DM) and ischemic stroke (IS) in recent years. However, it is unclear whether APOE gene polymorphisms are correlated with
Na Wang +7 more
doaj +1 more source
Development of a Melting Curve-Based Allele-Specific PCR of Apolipoprotein E (APOE) Genotyping Method for Genomic DNA, Guthrie Blood Spot, and Whole Blood. [PDF]
PLoS ONE, 2016 Genetic polymorphisms of apolipoprotein E (APOE) are associated with various health conditions and diseases, such as Alzheimer's disease, cardiovascular diseases, type 2 diabetes, etc.
Chia-Hsiang Chen
doaj +1 more source
GenoRisk: A polygenic risk score for Alzheimer's disease
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2021 Introduction Recent clinical trials are considering inclusion of more than just apolipoprotein E (APOE) ε4 genotype as a way of reducing variability in analysis of outcomes.
Samuel P. Dickson +10 more
doaj +1 more source
Biomédica: revista del Instituto Nacional de Salud, 2004 Varios estudios han demostrado la asociación de los polimorfismos de la apolipoproteína E (APO-E) con la osteoporosis, especialmente, la APO-E 4. Para analizar los polimorfismos APOE e identificar la asociación con variables clínicas y sociales, se ...
Elsa Villarreal, Antonio Bermúdez
doaj +1 more source
Codon 129 polymorphism of prion protein gene in is not a risk factor for Alzheimer's disease
Arquivos de Neuro-Psiquiatria, 2013 Interaction of prion protein and amyloid-b oligomers has been demonstrated recently. Homozygosity at prion protein gene (PRNP) codon 129 is associated with higher risk for Creutzfeldt-Jakob disease. This polymorphism has been addressed as a possible risk
Jerusa Smid +4 more
doaj +1 more source