Results 1 to 10 of about 45,778 (202)
The X-X-/E+E+ genotype of the XbaI/EcoRI polymorphisms of the apolipoprotein B gene as a marker of coronary artery disease in a Brazilian sample [PDF]
Brazilian Journal of Medical and Biological Research, 2003 Studies that consider polymorphisms within the apolipoprotein B (apo B) gene as risk factors for coronary artery disease (CAD) have reported conflicting results.
Antonio Pazin-Filho +2 more
exaly +8 more sources
Neural Regeneration Research, 2014 The apolipoprotein E gene ε4 allele is considered a negative factor for neural regeneration in late-onset Alzheimer's disease cases. The aim of this study was to establish a non-invasive, rapid method to genotype apolipoprotein E gene polymorphisms. Genomic DNA from mouth swab specimens was extracted using magnetic nanoparticles, and genotyping was ...
Yi, Li +4 more
openaire +3 more sources
Genes, 2023 The role of genetics as a predisposing factor related to an increased risk of developing long COVID symptomatology is under debate. The aim of the current secondary analysis was to identify the association between the Apolipoprotein E (ApoE) gene, a gene affecting cholesterol metabolism and previously associated with a higher risk of SARS-CoV-2 ...
Silvia Ambite Quesada +2 more
exaly +5 more sources
Apolipoprotein E ɛ3/ɛ4 genotype is associated with premature myocardial infarction: a hospital based retrospective study [PDF]
BMC Cardiovascular DisordersObjective To explore the association between apolipoprotein E (APOE) gene polymorphisms and the risk of premature (age of onset: men ≤ 55 years old, women ≤ 65 years old) myocardial infarction (PMI).
Hao Wang +6 more
doaj +2 more sources
Apolipoprotein E polymorphisms increase the risk of post-stroke depression
Neural Regeneration Research, 2016 Recent reports have shown that apolipoprotein E (APOE) polymorphisms are involved in neurodegenerative disease. However, it is unclear whether APOE affects post-stroke depression.
Xue-bin Li +6 more
doaj +2 more sources
The APOE paradox: divergent genetic influences on hemorrhagic stroke risk—A meta-analysis [PDF]
Frontiers in StrokeBackgroundApolipoprotein E (APOE) regulates lipid metabolism and neuronal repair, yet its alleles show contrasting effects on hemorrhagic stroke (HS) risk.
Manabesh Nath +3 more
doaj +2 more sources
APOE, Aβ42, and tau differentially impact cognitive decline in Sporadic, GBA1 and LRRK2 Parkinson’s disease [PDF]
npj Parkinson's DiseaseCognitive impairment varies across sporadic Parkinson’s disease (PD) and the common genetic subtypes glucocerebrosidase (GBA1) and leucine-rich repeat kinase 2 (LRRK2) PD and is influenced by Apolipoprotein E (APOE) polymorphisms and Alzheimer’s disease (
Ragasudha Botta +4 more
doaj +2 more sources
Frontiers in Endocrinology, 2022 Background Apolipoprotein E (APOE) gene mediates lipoprotein clearance and is one of the most studied candidate genes for type 2 diabetes mellitus (T2DM) and coronary artery disease (CAD).
Lei Wu +6 more
semanticscholar +1 more source
NAFLD‐related hepatocellular carcinoma: The growing challenge
Hepatology, EarlyView., 2022 Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah +2 more
wiley +1 more source
A rapid and cost-effective method for genotyping apolipoprotein E gene polymorphism [PDF]
Molecular Neurodegeneration, 2016 Apolipoprotein E (ApoE) is a major cholesterol carrier and plays an important role in maintaining lipid homeostasis both in the periphery and brain. Human APOE gene is polymorphic at two single nucleotides (rs429358 and rs7412) resulting in three different alleles (ε2, ε3 and ε4).
Zhong, Li +9 more
openaire +3 more sources