Results 21 to 30 of about 31,566,991 (117)

APOE genotype and entorhinal cortex volume in non-demented community-dwelling adults in midlife and early old age [PDF]

, 2012
Copyright © 2012 IOS PressThis article has been made available through the Brunel Open Access Publishing Fund.The apolipoprotein E (APOE) ε4 allele is a risk factor for the neuropathological decline accompanying Alzheimer's disease (AD) while, conversely,
Bunce, David, Perminder Sachdev, Cherbuin, N, Anstey, KJ, David Bunce, Kaarin J. Anstey, Bunce, D, Prapti Gautam, Simon Easteal, Gautam, P, Easteal, S, Cherbuin, Nicolas, Anstey, Kaarin, Gautam, Prapti, Sachdev, Perminder Singh, Nicolas Cherbuin, Sachdev, P, Easteal, Simon   +17 more
core   +1 more source

Association of apolipoprotein E gene polymorphism with gallstone disease in Iraqi Kurdish women

Iraqi Journal of Pharmaceutical Sciences
                Gallstone disease (GSD) is a worldwide problem; the frequency of GSD varies greatly amongst different ethnic groups, possibly due to environmental and genetic factors.
SEERWAN Raheem, Ismail Salih Kakey
doaj   +1 more source

Rapid determination of apolipoprotein E genotype using a heteroduplex generator

Journal of Lipid Research, 1999
The apoE gene exhibits two common polymorphisms that have been associated with both coronary artery disease and Alzheimer's disease. The polymorphisms create the three allelic isoforms E2, E3, and E4 which are encoded by Cys–Cys, Cys–Arg, and Arg–Arg at ...
M.K. Bolla, N. Wood, S.E. Humphries
doaj   +1 more source

APOE polymorphism and its effect on plasma C-reactive protein levels in a large general population sample [PDF]

, 2010
The literature on association between apolipoprotein E (APOE) gene variations and plasma levels of C-reactive protein (CRP) remains inconsistent, mainly due to low statistical power of previous studies.
Pikhart, H., Peasey, Anne, Pikhart, Hynek, Stavek, Petr, Hubacek, J.A., Kubinova, R., Marmot, Michael, Kubinova, Ruzena, Peasey, A., Hubacek, Jaroslav A., Marmot, M., Stavek, P., Bobak, Martin, Bobak, M.   +13 more
core   +1 more source

RELATIONSHIP OF APOLIPOPROTEIN A-1 GENE POLYMORPHISM WITH SOME GROWTH TRAITS OF COMMON CARP (CYPRINUS CARPIO L .)

The Iraqi Journal of Agricultural science
The study was conducted to investigate the relationship between the polymorphisms of A, B, C, D and E of the apolipoprotein A-1 (ApoA-1) gene with some traits (daily and total weight gain rate and feed conversion rate and efficiency) in 70 samples of ...
Othman M. Abdulmajeed, Mohammad S. Al-Khshali, Ahmed W. Al Ameri   +2 more
doaj   +1 more source

Preliminary evidence for an association between LRP-1 genotype and body mass index in humans. [PDF]

PLoS ONE, 2012
The LDL receptor-related protein-1 gene (LRP-1) has been associated with obesity in animal models, but no such association has yet been reported in humans.
Alexis C Frazier-Wood, Edmond K Kabagambe, Ingrid B Borecki, Hemant K Tiwari, Jose M Ordovas, Donna K Arnett   +5 more
doaj   +1 more source

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub, Armin Sepp, Amin Rostami‐Hodjegan, Brahim Achour   +3 more
wiley   +1 more source

Endothelial nitric oxide synthase genotype and ischemic heart disease: meta-analysis of 26 studies involving 23028 subjects [PDF]

, 2004
Background: Polymorphisms in the endothelial nitric oxide synthase (eNOS) gene may influence the risk of ischemic heart disease (IHD), but data from published studies with individually low statistical power are conflicting.
Humphries, S.E., Bautista, Leonelo E, Humphries, Steve E, Bautista, L.E., Casas, J.P., Hingorani, Aroon D, Casas, Juan P, Hingorani, A.D., J. P. Casas   +8 more
core   +1 more source

Polymorphisms in the genes of citohrom oxidase P450 2D6 (CYP2D6), paraoxonase 1 (PON1) and apolipoproteine E (APOE) as risk factors for Parkinson's disease [PDF]

Vojnosanitetski Pregled, 2007
Background/Aim. The presence of Parkinson's disease (PD) among the members of a family is a clear indication of the significance of genetics in its development.
Đurić Gordana, Svetel Marina, Illarioškin Nikolaevič Sergej, Dragađević Nataša, Gavrilović Jelena, Kostić Vladimir S.   +5 more
doaj   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source