Results 51 to 60 of about 349,657 (299)
Advances in Materials Science and EngineeringThe pharmaceutical industry is looking for new and innovative ways of manufacturing to improve product quality and reduce process complexity. In manufacturing oral solid dosage products, blending is a crucial step in ensuring the homogeneity of active ...
Sumit Kumar +5 more
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Continuous direct compression as manufacturing platform for sustained release tablets [PDF]
, 2017 This study presents a framework for process and product development on a continuous direct compression manufacturing platform. A challenging sustained release formulation with high content of a poorly flowing low density drug was selected.
Cunningham, C. +7 more
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
A Phenomenology of ‘Blending in’: Beyond Emotional Regulation
Interpersona: An International Journal on Personal Relationships, 2018 The phenomenon of devaluing of self for adolescent girls has been highlighted in previous qualitative research in a US cultural context. Carol Gilligan and her colleagues have documented a loss of connection to self and loss of voice.
Katie Creighton, Paul Downes
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OENO One, 2022 Thirty-nine Champagnes from six different brands originating from the AOC Champagne area were analyzed for major and trace element concentrations in the context of their production processes and in relation to their geographical origins.
Robin Cellier +8 more
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A continues multi-material toolpath planning for tissue scaffolds with hollowed features [PDF]
, 2011 This paper presents a new multi-material based toolpath planning methodology for porous tissue scaffolds with multiple hollowed features. Ruled surface with hollowed features generated in our earlier work is used to develop toolpath planning.
Bahattin Koc +7 more
core +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Correspondence Theory and Phonological Blending in French
SHS Web of Conferences, 2014 Though less productive than rival word-formation processes like compounding and affixation, blending is still a rich source of neologisms in French. Despite this productivity, however, blends are often seen by scholars as unpredictable, uninteresting ...
Lee Scott
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Postponement for greener skies: the potential for sustainable aviation fuel on-site blending at airports [PDF]
Logistics ResearchPurposeSustainable Aviation Fuel (SAF) is crucial for aviation decarbonization, but its current pre-blending process at refineries presents challenges, including fixed blending ratios, higher transportation costs and long lead times.
Martin Oetzel, Puay Guan Goh, Kai Hoberg
doaj +1 more source