Results 31 to 40 of about 44 (44)
ILC2 Diversity, Location, and Function in Pulmonary Disease
ABSTRACT Type‐2 inflammation is driven by the production of canonical type‐2 cytokines IL‐4, IL‐5, and IL‐13. Type‐2 cytokines promote mucus production, innate immune cell recruitment, and smooth muscle contractility in mucosal tissues. These hallmarks of type‐2 inflammation are important contributors to the weep‐and‐sweep responses observed in the ...
Mukesh Verma+2 more
wiley +1 more source
ABSTRACT The thymus is a primary lymphoid organ for generating a diverse yet self‐tolerant T cell repertoire. Among the thymic stromal cells that create the thymic microenvironment, thymic epithelial cells (TECs) have received the most attention because of their distinctive functions in the repertoire selection of T cells. Other types of thymic stromal
Ryunosuke Muro, Takeshi Nitta
wiley +1 more source
The complexity of indole‐3‐acetic acid's (IAA's) role in human health and disease. IAA is a multifaceted compound with significant consequences for several physiological and pathological processes. ABSTRACT Indole‐3‐acetic acid (IAA) is recognized as a common plant growth hormone.
Nargis Shaheen+4 more
wiley +1 more source
Hybrid Molecules as Efficient Drugs against Multidrug‐Resistant Malaria Parasites
Among hybrid molecules currently developed as antimalarial drug candidates, emoquine‐1 exhibits high activity against all the multidrug‐resistant Plasmodium strains tested up to now, including artemisinin‐resistant quiescent parasites, critical parameters for promising antimalarial drugs. It is also curative in mouse malaria.
Anne Robert+6 more
wiley +1 more source
Esophageal cancer is a highly aggressive malignant tumor of the digestive tract with a generally poor prognosis, and its incidence and mortality rates remain high globally. Radiotherapy serves as the cornerstone of esophageal cancer treatment, while the emergence of immunotherapy has brought unprecedented changes to the treatment landscape of ...
Guohui Liu+3 more
wiley +1 more source
ABSTRACT Background Standardized surgical approaches to advanced pre‐auricular cutaneous squamous cell carcinomas (cSCC) are lacking. Methods Fifty–four patients who underwent lateral temporal bone resection (LTBR) for pre‐auricular cSCC were grouped into “Levels” of increasing disease spread.
Michael Schachtel+4 more
wiley +1 more source
Cancer therapy and reproductive impact
Abstract All patients where the cancer treatment has gonadotoxic potential should be referred for oncofertility advice. The effect of chemotherapy and radiotherapy on the human ovary can vary from no impact to full‐blown premature ovarian failure due to hormonal and follicular depletion.
Dov Feldberg, Nikhil Purandare
wiley +1 more source
Pregnancy after cancer: FIGO Best practice advice
Abstract Advances in cancer care have led to a growing number of cancer survivors globally. As cancer increasingly affects women and people of reproductive age, more individuals will be experiencing pregnancy after completing cancer treatment. This Best Practice Advice manuscript describes the epidemiology of pregnancy after cancer, recommended ...
Cynthia Maxwell+23 more
wiley +1 more source
Transthoracic Drainage of an Intrapulmonary Bronchogenic Cyst With an Intercostal Catheter
We present the case of an 84‐year‐old female with a large intrapulmonary bronchogenic cyst who presented with progressive dyspnoea, haemoptysis, and fevers. Due to relative contraindications for surgery, an ultrasound‐guided percutaneous intercostal catheter insertion with administration of fibrinolytic and mucolytic therapy was performed to evacuate ...
Khuyen Hoang+3 more
wiley +1 more source