The cryptonephridial/rectal complex: an evolutionary adaptation for water and ion conservation. [PDF]
Beaven R, Denholm B.
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Pollen beetle (Astylus atromaculatus)-associated gastroenteric disease in cattle: report of 6 natural outbreaks. [PDF]
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Carbon, climate, and natural disturbance: a review of mechanisms, challenges, and tools for understanding forest carbon stability in an uncertain future. [PDF]
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Mylabris: a review of its biological characteristics, chemical composition, pharmacological, toxicology, pharmacokinetics, and marketed drugs. [PDF]
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On the history, synthesis, and medicinal use of cantharidin, LB-100, and their analogs. [PDF]
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Stability analysis of reference genes in Maconellicoccus hirsutus across various conditions including dsRNA treatment. [PDF]
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Ingestion of a Blister Beetle (Mecoidae Family)
Pediatrics, 1996Cantharidin, the most important active principle of Cantharis vesicatoria (Spanish fly), has a long history. It is a medieval medicine, considered over a hundred years ago as the most powerful medicine on the Materia Medica. It has been used as a skin irritant, vessicant, and abortifacient, and has long been wrongly considered an aphrodisiac.1
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Staphylinid blister beetle dermatitis
Contact Dermatitis, 2002Valeria Brazzelli
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BLISTER bugs are found throughout the United States and southern Canada. In Europe the best known of the blister beetles is called the Spanish fly (Cantharis vesicatoria); it occurs in great numbers in France and Spain. More than 200 species have been described, the greatest number being found in southwestern and western United States.
C F, LEHMANN, J L, PIPKIN, A C, RESSMANN
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Cantharidin production in a blister beetle
Experientia, 1993Cantharidin, a potent defensive chemical, is present in all ten life stages of the blister beetle Epicauta funebris. The first five larval stages accumulate cantharidin as they feed and grow in size. When disturbed, they exude cantharidin in a milky oral fluid, not in hemolymph which adult beetles reflexively discharge from leg joints.
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