Case Report: Persistent toxic reactions in a toddler with a negative blood cantharidin toxicology test [PDF]
Frontiers in PediatricsCantharidin is a potent natural toxin and has been used in traditional Chinese medicine to treat cancers and various ailments such as rabies or psoriasis. However, improper use of cantharidin can easily lead to poisoning.
Zhuyan Duan +7 more
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Molecules, 2017 PEGylated liposomes have received much attention as pharmaceutical carriers to deliver chemotherapeutic agents for therapeutic purpose. The aim of this study was to prepare and characterize PEGylated liposome of cantharidin and investigate its ...
Hong-Qi Zhang, Xue ZHANG, Zhijun Yang
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Transcriptomics, Proteomics and Network Pharmacology Reveal the Mechanisms of Cantharidin-Induced Kidney Injury in Rats [PDF]
Current Issues in Molecular BiologyCantharidin (CTD), the principal active constituent of the traditional Chinese medicine (TCM) Mylabris, exhibits potent antitumor activity. However, its clinical application is limited by organ toxicity (especially nephrotoxicity), and the underlying ...
Xiaotong Duan +7 more
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Cantharidin: a double-edged sword in medicine and toxicology [PDF]
Frontiers in PharmacologyCantharidin (CTD), a natural terpenoid toxin secreted by blister beetles, acts as a potent inhibitor of protein phosphatase. As the principal active component of Mylabris, a traditional Chinese medicine, CTD has attracted considerable interest due to its
Jie Zhang +7 more
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The Effectiveness of Topical Treatment for Plantar Warts: A Retrospective Cohort Study [PDF]
Infectious Disease ReportsBackground: Plantar warts, caused by human papillomavirus (HPV), are a common condition that can be painful and resistant to treatment. There are various therapeutic options for managing them, but it is not always clear which are the most effective and ...
Ana Mª Rayo Pérez +3 more
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Cantharidin overcomes IL-2Rα signaling-mediated vorinostat resistance in cutaneous T-cell lymphoma through reactive oxygen species [PDF]
Journal for ImmunoTherapy of CancerBackground Vorinostat (SAHA) is a histone deacetylase inhibitor that has shown clinical efficacy against advanced cutaneous T-cell lymphoma (CTCL). However, only a subset of patients with CTCL (30–35%) respond to SAHA and the response is not always ...
Hongmei Zhang +9 more
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Research Progress on Multiple Organ Damage and Mechanism of Cantharidin Poisoning [PDF]
Fayixue Zazhi, 2020 Cantharidin poisoning has been proven to cause multiple organ damage. Acute circulatory failure, acute renal failure, and multiple organ failure resulting from cantharidin poisoning are the main causes of death for patients with cantharidin poisoning ...
ZHANG You-you, YU Ya-lei, ZHANG Jie,et al
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Pakistan Journal of Pharmaceutical Sciences, 2022 Cantharidin is a natural compound with cardiotoxicity. Cellular senescence and senescence-associated secretory phenotype (SASP) are implicated in chemotherapy-associated cardiotoxicity.
Yujing Shi, Yi Lv, Qi You, Weidong Qian
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Cantharidin downregulates PSD1 expression and inhibits autophagic flux in yeast cells
FEBS Open Bio, 2022 Cantharidin is a terpenoid compound of insect origin, naturally produced by male blister beetles as an antipredatory mechanism. Cantharidin has anticancer properties, which are attributed to its ability to induce cell cycle arrest, DNA damage, MAPK ...
Swati Swagatika, Raghuvir Singh Tomar
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De Novo Transcriptome and Expression Profile Analysis to Reveal Genes and Pathways Potentially Involved in Cantharidin Biosynthesis in the Blister Beetle Mylabris cichorii. [PDF]
PLoS ONE, 2016 The dried body of Mylabris cichorii is well-known Chinese traditional medicine. The sesquiterpenoid cantharidin, which is secreted mostly by adult male beetles, has recently been used as an anti-cancer drug.
Yi Huang +8 more
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