Results 21 to 30 of about 4,608 (205)
Pakistan Journal of Pharmaceutical Sciences, 2022 Cantharidin is a natural compound with cardiotoxicity. Cellular senescence and senescence-associated secretory phenotype (SASP) are implicated in chemotherapy-associated cardiotoxicity.
Yujing Shi, Yi Lv, Qi You, Weidong Qian
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Cantharidin downregulates PSD1 expression and inhibits autophagic flux in yeast cells
FEBS Open Bio, 2022 Cantharidin is a terpenoid compound of insect origin, naturally produced by male blister beetles as an antipredatory mechanism. Cantharidin has anticancer properties, which are attributed to its ability to induce cell cycle arrest, DNA damage, MAPK ...
Swati Swagatika, Raghuvir Singh Tomar
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De Novo Transcriptome and Expression Profile Analysis to Reveal Genes and Pathways Potentially Involved in Cantharidin Biosynthesis in the Blister Beetle Mylabris cichorii. [PDF]
PLoS ONE, 2016 The dried body of Mylabris cichorii is well-known Chinese traditional medicine. The sesquiterpenoid cantharidin, which is secreted mostly by adult male beetles, has recently been used as an anti-cancer drug.
Yi Huang +8 more
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Cantharidin Induced Oral Squamous Cell Carcinoma Cell Apoptosis via the JNK-Regulated Mitochondria and Endoplasmic Reticulum Stress-Related Signaling Pathways. [PDF]
PLoS ONE, 2016 Oral cancer is a subtype of head and neck cancer which represents 2.65% of all human malignancies. Most of oral cancer is histopathologically diagnosed as oral squamous cell carcinoma (OSCC). OSCC is characterized by a high degree of local invasion and a
Chin-Chuan Su +5 more
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Acta Agriculturae Slovenica, 2020 Cantharidin and its analog, endothall, are known to have phytotoxic effects and their mechanism of action involves the inhibition of phosphatases. Enzymes and antioxidant compounds act as barriers against phytotoxic compounds. Catalase and peroxidase are
Yalda GHOTBZADEH KERMANI +3 more
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Animals, 2021 True blister beetles (genus Epicauta, family Meloidae) produce cantharidin, which can cause toxicosis in humans and animals. Some recent reports suggest that poisoning by the blister beetle has occurred in the Mediterranean part of Slovenia, which has ...
Breda Jakovac-Strajn +5 more
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Molecules, 2017 PEGylated liposomes have received much attention as pharmaceutical carriers to deliver chemotherapeutic agents for therapeutic purpose. The aim of this study was to prepare and characterize PEGylated liposome of cantharidin and investigate its ...
Xue Zhang +5 more
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Investigation of Abundance and Diversity of Cantharidin Compounds in the Hycleus colligatus, Mylabris schrenki, Mylabris cincta, and Hycleus schah Species from Kerman Province, Iran [PDF]
Journal of Genetic ResourcesCantharidin and cantharidin-related compounds (CRCs) are synthesized by Meloidae to defend against predators. Also, Cantharidin and CRCs are known as biopesticides.
Sara sadat Nezhad-ghaderi +2 more
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BMC Complementary Medicine and Therapies, 2023 Background Cantharidin (CTD) is a major ingredient of cantharis ( Mylabris phalerata Pallas) and has been used extensively in traditional Chinese medicines.
Jia Yan +6 more
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Hepatotoxic mechanism of cantharidin: insights and strategies for therapeutic intervention
Frontiers in Pharmacology, 2023 Cantharidin (CTD), a natural compound derived from Mylabris, is widely used in traditional Oriental medicine for its potent anticancer properties. However, its clinical application is restricted due to its high toxicity, particularly towards the liver ...
D. Jin, Nana Huang, Jingsun Wei
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