Results 31 to 40 of about 4,608 (205)

Characterization of Juvenile Hormone Related Genes Regulating Cantharidin Biosynthesis in Epicauta chinensis

open access: yesScientific Reports, 2017
Cantharidin is a defensive toxin biosynthesized by blister beetles. It is well known for medical applications and toxicity. However, the biosynthesis process of cantharidin is still not well understood.
Ming Jiang, Shumin Lü, Yalin Zhang
doaj   +1 more source

Cantharidin and sodium fluoride attenuate the negative inotropic effects of carbachol in the isolated human atrium

open access: yesNaunyn-Schmiedeberg's Archives of Pharmacology, 2023
Carbachol, an agonist at muscarinic receptors, exerts a negative inotropic effect in human atrium. Carbachol can activate protein phosphatases (PP1 or PP2A). We hypothesized that cantharidin or sodium fluoride, inhibitors of PP1 and PP2A, may attenuate a
R. Schwarz   +3 more
semanticscholar   +1 more source

Chemosensory System Decoding: Transcriptome-Wide Identification and Expression Profiling of Olfactory Genes in <i>Lytta sifanica</i>. [PDF]

open access: yesEcol Evol
Lytta sifanica (Coleoptera: Meloidae), a species of significant economic importance, is renowned for its production of the toxic compound cantharidin. In this research, Zhou and colleagues collected specimens of this insect and identified seventy olfactory‐related genes through transcriptomic analysis of adult antennae in L. sifanica. Sequence homology
Zhou F   +9 more
europepmc   +2 more sources

Males of a strongly polygynous species consume more poisonous food than females. [PDF]

open access: yesPLoS ONE, 2014
We present evidence of a possible case of self-medication in a lekking bird, the great bustard Otis tarda. Great bustards consumed blister beetles (Meloidae), in spite of the fact that they contain cantharidin, a highly toxic compound that is lethal in ...
Carolina Bravo   +4 more
doaj   +1 more source

Chronic Sublethal Effects of Cantharidin on the Diamondback Moth Plutella xylostella (Lepidoptera: Plutellidae)

open access: yesToxins, 2015
The diamondback moth, Plutella xylostella (Linnaeus) (Lepidoptera: Plutellidae), is a major pest of cruciferous vegetables worldwide. Cantharidin, a natural toxin isolated from blister beetles, has been reported to be toxic to P. xylostella.
Zhengyu Huang, Yalin Zhang
doaj   +1 more source

The anti-hepatocellular carcinoma effect of aidi injection was related to the synergistic action of cantharidin, formononetin, and isofraxidin through BIRC5, FEN1, and EGFR.

open access: yesJournal of Ethnopharmacology, 2023
ETHNOPHARMACOLOGICAL RELEVANCE Aidi injection (ADI) is a popular anti-tumor Chinese patent medicine, widely used in clinics for the treatment of hepatocellular carcinoma (HCC) with remarkable therapeutic effects through multiple targets and pathways ...
Shan Lu   +18 more
semanticscholar   +1 more source

Origin, transfer and distribution of cantharidin-related compounds in the blister beetle Hycleus scabiosae

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2012
Cantharidin provides chemical protection for the coleopteran families Meloidae and Oedemeridae. In the present study, it was observed that cantharidin concentration in Hycleus scabiosae was slightly decreased from mated females (mean = 0.011 mg/mg of dry
MR Nikbakhtzadeh   +3 more
doaj   +1 more source

Cantharidin and Its Analogue Norcantharidin Inhibit Metastasis—Inducing Genes S100A4 and MACC1

open access: yesInternational Journal of Molecular Sciences, 2023
Colorectal cancer (CRC) is the third most prevalent and second deadliest cancer worldwide. In addition, metastasis directly causes up to 90% of all CRC deaths, highlighting the metastatic burden of the disease.
P. Schöpe   +7 more
semanticscholar   +1 more source

Use of different ligand modification liposomes to evaluate the anti-liver tumor activity of cantharidin

open access: yesJournal of liposome research, 2023
In this study, cantharidin(CTD), a bioactive terpenoid in traditional Chinese medicine cantharidin, was selected as a model component to construct novel nano liposome delivery systems for hepatocellular carcinoma therapy. Previous studies have shown that
Manshu Zou   +4 more
semanticscholar   +1 more source

Detection of cantharidin-related compounds in Mylabris impressa (Coleoptera: Meloidae)

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2007
Cantharidin is mainly found in the beetle families Meloidae and Oedemeridae (Insecta: Coleoptera) which are the natural producers of this terpene anhydride.
M. R. Nikbakhtzadeh, B. Ebramihi
doaj   +1 more source

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