Results 41 to 50 of about 4,608 (205)
A systems biology approach reveals the role of a novel methyltransferase in response to chemical stress and lipid homeostasis. [PDF]
PLoS Genetics, 2011 Using small molecule probes to understand gene function is an attractive approach that allows functional characterization of genes that are dispensable in standard laboratory conditions and provides insight into the mode of action of these compounds ...
Elena Lissina +14 more
doaj +1 more source
Cantharidin increases the force of contraction and protein phosphorylation in isolated human atria
Naunyn-Schmiedeberg's Archives of Pharmacology, 2023 Cantharidin, an inhibitor of protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A), is known to increase the force of contraction and shorten the time to relaxation in human ventricular preparations.
R. Schwarz +3 more
semanticscholar +1 more source
Frontiers in Pharmacology, 2019 Aerobic glycolysis plays a decisive role in cancer growth. However, its role in cancer metastasis was rarely understood. Cantharidin a natural compound from an arthropod insect cantharis exerts potent anticancer activity.
Yanhong Pan +11 more
doaj +1 more source
Bioorganic & Medicinal Chemistry Letters, 2023 Natural product cantharidin can inhibit multiple myeloma cell growth in vitro, while serious adverse effects limited its clinical application. Therefore, the structural modification of cantharidin is needed.
Sanfeng Dong +15 more
semanticscholar +1 more source
The protective effect of L-glutamine against acute Cantharidin-induced Cardiotoxicity in the mice
BMC Pharmacology and Toxicology, 2020 Background Cantharidin (CTD) is a compound which have the potential to be exploited as an antitumor drug, and it has been demonstrated antitumor effects in a variety of cancers. However, the use is limited due to its severe toxicity. It has reported that
Haozhen Shao +4 more
doaj +1 more source
Molecules, 2012 Cantharidin, an active component in mylabris, is used in traditional Chinese medicine (TCM) to treat scabies and hepatoma, but accompanied by hemorrhagic cystitis.
Li-Chun Lin +6 more
doaj +1 more source
"Cantharidin Component of Iranian Blister Beetles (Col: Meloidae) and their differences between Iranian and Exotic Species" [PDF]
Iranian Journal of Public Health, 2002 Cantharidin is one of the most well- known compounds which has ever been fascinating in medicine due to its effects on human and domestic animals. It is produced naturally by beetles of family Meloidae and Oedemeridae, however a considerable spectra of ...
MR Nikbakhtzadeh, S Tirgari
doaj +2 more sources
The European Zoological Journal, 2022 The new species Atrichopogon (Atrichopogon) tolfensis n. sp. from Tolfa Mountains (Italy, Latium, and Rome) is described and illustrated. Both sexes of the species were collected using cantharidin-baited traps from June 2020 to January 2021.
R. Szadziewski +3 more
doaj +1 more source
Biomolecules, 2023 The diamondback moth is a detrimental insect pest of brassicaceous crops which was among the first crop insects to be reported as DDT resistant. It has since proven to be significantly resistant to nearly every synthetic insecticide used in the field in ...
Kwan-Gu Lee +7 more
semanticscholar +1 more source
Antiparasitic Effects of Potentially Toxic Beetles (Tenebrionidae and Meloidae) from Steppe Zones
Toxins, 2021 Arthropods and specifically beetles can synthesize and/or sequester metabolites from dietary sources. In beetle families such as Tenebrionidae and Meloidae, a few studies have reported species with toxic defensive substances and antiparasitic properties ...
Marta Díaz-Navarro +8 more
doaj +1 more source