Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Quality Control and Traceability Framework of Electrochromic Materials Based on Block Chain from the Perspective of Practical Application. [PDF]
Comput Intell Neurosci, 2022 Wang Q, Li J, Zheng M, Ma X, Wang B.
europepmc +1 more source
Knowledge acquisition in supply chain partnerships: the role of power [PDF]
, 2012 Knowledge is recognised as an important source of competitive advantage and hence there has been increasing academic and practitioner interest in understanding and isolating the factors that contribute to effective knowledge transfer between supply chain
Ghobadian, A +8 more
core +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
A Novel Block Chain Method for Urban Digitization Governance in Birth Registration Field: A Case Study. [PDF]
Int J Environ Res Public Health, 2022 Shi J, Danquah SKN, Dong W.
europepmc +1 more source
Teaching in the block: perceptions from an agricultural education classroom [PDF]
, 2002 Plan BA relatively new initiative called block scheduling is being used in high schools all over the country. Several schools are investigating and adopting block schedules to replace traditional schedules.
Spoelstra, Elizabeth
core
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Big data exchange based on information chain
Dianxin kexue, 2016 The flow and sharing of data is the foundation of the development of big data industry. However, facing with the specification of data itself and many problems that data trading modes have, the development of data flow and sharing moves slowly.
Nan LIU, Jinwu WEI, Lu LIU
doaj
A New Double-Layer Decentralized Consistency Algorithm for the Multi-Satellite Autonomous Mission Allocation Based on a Block-Chain. [PDF]
Sensors (Basel), 2022 Cheng F, Ning X, Dong Y.
europepmc +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source