Results 91 to 100 of about 1,019,943 (288)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
LBlock: A Lightweight Block Cipher [PDF]
, 2011 In this paper, we propose a new lightweight block cipher called LBlock. Similar to many other lightweight block ciphers, the block size of LBlock is 64-bit and the key size is 80-bit. Our security evaluation shows that LBlock can achieve enough security margin against known attacks, such as differential cryptanalysis, linear cryptanalysis, impossible ...
Wenling Wu, Lei Zhang 0012
openaire +3 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Statistical assessment – as a part of security assessment applied to a block cipher [PDF]
Revista Română de Statistică, 2016 The security provided by the block cipher algorithms is a top modern approached issue within the specific researches. The security assessment of a block algorithm involves the assessing and testing of components, the statistical testing of algorithm and ...
Ioana Roxana Dragomir, Marilena Lazăr
doaj
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
New Methodology of Block Cipher Analysis Using Chaos Game
Journal of ICT Research and Applications, 2014 Block cipher analysis covers randomness analysis and cryptanalysis. This paper proposes a new method potentially used for randomness analysis and cryptanalysis.
Budi Sulistyo +3 more
doaj
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Impossible Boomerang Attack for Block Cipher Structures [PDF]
, 2009 Impossible boomerang attack \cite{lu} (IBA) is a new variant of differential cryptanalysis against block ciphers. Evident from its name, it combines the ideas of both impossible differential cryptanalysis and boomerang attack. Though such an attack might
Huihui Yap, Jiali Choy
core +1 more source