Results 71 to 80 of about 44,791 (329)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

New Methodology of Block Cipher Analysis using Chaos Game [PDF]

open access: yesITB Journal of Information and Communication Technology, 2011
Block cipher analysis covers randomness analysis and cryptanalysis. This paper proposes a new method potentially used for randomness analysis and cryptanalysis. The method uses true random sequence concept as a reference for measuring randomness level of
Budi Sulistyo   +3 more
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Systematization of a 256-bit lightweight block cipher Marvin [PDF]

open access: yes, 2018
In a world heavily loaded by information, there is a great need for keeping specific information secure from adversaries. The rapid growth in the research field of lightweight cryptography can be seen from the list of the number of lightweight stream as ...
Bhattacharya, Abhishek   +2 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Elastic Block Ciphers

open access: yes, 2004
We introduce a new concept of elastic block ciphers, symmetric-key encryption algorithms that for a variable size input do not expand the plaintext, (i.e., do not require plaintext padding), while maintaining the diffusion property of traditional block ciphers and adjusting their computational load proportionally to the size increase.
Cook, Debra L.   +2 more
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Likelihood Estimation for Block Cipher Keys [PDF]

open access: yes, 1995
In this paper, we give a general framework for the analysis of block ciphers using the statistical technique of likelihood estimation. We show how various recent successful cryptanalyses of block ciphers can be regarded in this framework.
Murphy, Sean   +3 more
core   +1 more source

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