Results 121 to 130 of about 1,019,943 (288)

HISEC: a new lightweight block cipher algorithm

open access: yes, 2014
Lightweight block cipher algorithms are vital for constrained environment. There are many applications need secured lightweight block cipher algorithm like credit card, E-passport and etc.
Alshaikhli, Imad Fakhri Taha   +2 more
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

The Large Block Cipher Vistrutah

open access: yesIACR Transactions on Symmetric Cryptology
Vistrutah is a block cipher with block sizes of 256 and 512 bits. It iterates a step function consisting of two AES rounds applied to each 128-bit block of the state, followed by a state-wide cell permutation. Building upon established design principles from Simpira, Haraka, Pholkos, and ASURA, Vistrutah leverages AES instructions to achieve high ...
Avanzi, Roberto   +3 more
openaire   +2 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Likelihood Estimation for Block Cipher Keys [PDF]

open access: yes, 1995
In this paper, we give a general framework for the analysis of block ciphers using the statistical technique of likelihood estimation. We show how various recent successful cryptanalyses of block ciphers can be regarded in this framework.
Walker, Michael   +4 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Block Cipher Based on Randomly Generated Quasigroups

open access: yes, 2010
Quasigroups are algebraic structures closely related to Latin squares which have many different applications. The construction of block cipher is based on quasigroup string transformation.
Deepthi Haridas   +2 more
core   +1 more source

FPE scheme based on k-splits Feistel network

open access: yesTongxin xuebao, 2012
The construction features and discipline of Feistel network-based FPE(format-preserving encryption)schemes were analyzed.Considering on the problem that 2-splits Feistel networks-based FPE cipher’s block size was in narrow range,a type-2 Feistel network ...
Jing-wei LI   +3 more
doaj   +2 more sources

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