Results 141 to 150 of about 2,707,155 (337)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

PENGAMANAN PESAN TEKS DENGAN KRIPTOGRAFI LIGHTWEIGHT PRESENT CIPHER PADA CIPHER BLOCK CHAINING [PDF]

open access: yes
Algoritma kriptografi lightweight dirancang sedemikian sehingga dapat diterapkan pada suatu perangkat IoT yang terbatas. Salah satu cipher yang termasuk ke dalam kriptografi lightweight adalah Present Cipher.
Reksa Alamsyah, -
core  

CRITERIA FOR MARKOV BLOCK CIPHERS

open access: yesPrikladnaya diskretnaya matematika, 2018
Summary: We study probabilistic models of block ciphers with random independent identically distributed round keys. We call they Markov ciphers if sequence of round differentials is a simple homogeneous Markov chain. Criteria and sufficient condition for this property are adjusted and generalized.
openaire   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

The Large Block Cipher Vistrutah

open access: yesIACR Transactions on Symmetric Cryptology
Vistrutah is a block cipher with block sizes of 256 and 512 bits. It iterates a step function consisting of two AES rounds applied to each 128-bit block of the state, followed by a state-wide cell permutation. Building upon established design principles from Simpira, Haraka, Pholkos, and ASURA, Vistrutah leverages AES instructions to achieve high ...
Avanzi, Roberto   +3 more
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

3rd IEEE International Conference on Computer and Communication Systems (ICCCS 2018)

open access: yes, 2018
Block cipher encryption works on fixed length blocks, usually 128bits. The blocks of data are transformed into encrypted data blocks of identical size using a shared session key.
Sahi, Aqeel, Li, Yan, Lai, David
core  

A block cipher based on genetic algorithm [PDF]

open access: yes, 2016
The development of block ciphers have resulted in a number of cryptographic algorithms such as, AES, ARIA, BLOWFISH256, DESL, 3D-AES and many more.
Zakaria, Nur Hafiza
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

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