Results 71 to 80 of about 44,265 (336)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Software system of cryptanalysis using impossible differentials method based on parallel programming technologies OpenMP and MPI [PDF]
, 2013 Програма, яка розробляється в даному проекті, призначена для проведення криптоаналізу методом неможливих диференціалів блокового симетричного шифру AES, а саме – над елементами раунду.The program is being developed in this project is designed for ...
Novak, Nazarii +1 more
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
, 2004 We introduce a new concept of elastic block ciphers, symmetric-key encryption algorithms that for a variable size input do not expand the plaintext, (i.e., do not require plaintext padding), while maintaining the diffusion property of traditional block ciphers and adjusting their computational load proportionally to the size increase.
Cook, Debra L. +2 more
openaire +2 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
An Enhanced Dataflow Analysis to Automatically Tailor Side Channel Attack Countermeasures to Software Block Ciphers [PDF]
, 2017 Protecting software implementations of block ciphers from side channel attacks is a significant concern to realize secure embedded computation platforms.
Barenghi, Alessandro, Pelosi, Gerardo
core
Perfect Block Ciphers with Small Blocks [PDF]
, 2007 Existing symmetric encryption algorithms target messages consisting of elementary binary blocks of at least 64 bits. Some applications need a block cipher which operates over smaller and possibly nonbinary blocks, which can be viewed as a pseudo-random permutation of n elements.
Louis Granboulan, Thomas Pornin
openaire +1 more source