Results 121 to 130 of about 1,011,747 (284)

AES Security Improvement by Utilizing New Key-Dependent XOR Tables

IEEE Access
Increasing the security of block ciphers is a topic of great interest today, and thus there is a variety of work to enhance the strength of such ciphers.
Tran Thi Luong, Nguyen Ngoc Cuong, Bay Vo   +2 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Block ciphers sensitive to Gröbner Basis Attacks

, 2005
We construct and analyze Feistel and SPN ciphers that have a sound design strategy against linear and differential attacks but for which the encryption process can be described by very simple polynomial equations. For a block and key size of 128 bits, we
Johannes Buchmann, Andrei Pychkine, Ralf-Philipp Weinmann, Pyshkin, Andrei, Weinmann, Ralf-Philipp, Andrei Pyshkin, Buchmann, Johannes   +6 more
core   +1 more source

Cryptanalysis of lightweight block ciphers

, 2011
One of the ways to provide information security is cryptography. Traditionally, cryptographic operations as encryption of data have been applied to protect the information contained in a centralized and powerful computing environment.
Jha, Vikash Kumar
core   +1 more source

CRITERIA FOR MARKOV BLOCK CIPHERS

Prikladnaya diskretnaya matematika, 2018
Summary: We study probabilistic models of block ciphers with random independent identically distributed round keys. We call they Markov ciphers if sequence of round differentials is a simple homogeneous Markov chain. Criteria and sufficient condition for this property are adjusted and generalized.
openaire   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Combined attacks on block ciphers

, 2009
Cryptanalytic methods are very important tools in terms of evaluating the security of block ciphers in a more accurate and reliable way. Differential and linear attacks have been the most effective cryptanalysis methods since the early 1990s. However, as
NEŞE ÖZTOP
core  

Design of a Linear Layer Optimised for Bitsliced 32-bit Implementation

IACR Transactions on Symmetric Cryptology
The linear layer of block ciphers plays an important role in their security In particular, ciphers designed following the wide-trail strategy use the branch number of the linear layer to derive bounds on the probability of linear and differential trails.
Gaëtan Leurent, Clara Pernot
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source