Results 81 to 90 of about 2,917,992 (321)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Communication-radar coexistence design based on block diagonalization
Tongxin xuebao, 2021 Aiming at the problem of coexistence of communication and radar at the same frequency， a block diagonalization design scheme was proposed.Firstly， an optimization problem was established to maximum the communication system’s sum rate subject to no ...
Kaifeng HAN +3 more
doaj +2 more sources
The contribution of digital tools to architectural design studio: A case study
Ain Shams Engineering JournalThe relationship between digital tools and architectural education grows stronger each day. In addition to the increase in the number and variation of computer aided design software, the emergence of alternative tools for research and visual ...
Salih Ceylan +4 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Mud-concrete block (MCB): mix design & durability characteristics
Case Studies in Construction Materials, 2018 Mud-Concrete is a novel concept which employs a form of ‘Concrete’ produced using soil, cement and water. The initial concept of developing Mud-Concrete was to incorporate both the strength and durability of concrete into mud-based constructions to ...
F.R. Arooz, R.U. Halwatura
doaj +1 more source
Cyclic Block Designs With Block Size 3
European Journal of Combinatorics, 1981 We prove that the necessary conditions for the existence of cyclic block designs with block size 3 are sufficient with two exceptions.
Colbourn, Marlene J. +1 more
openaire +1 more source
Acoustic Insulation Characteristics and Optimal Design of Membrane-Type Metamaterials Loaded with Asymmetric Mass Blocks [PDF]
, 2023 Renjie Jiang +4 more
openalex +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Computers in Human Behavior ReportsNew technologies, such as VR and AR, allow individuals to interact with digital avatars in increasingly realistic ways. As these applications become more widespread, it is important to understand how humans perceive 3D avatars and their facial features ...
Yuqian Wang, Xinyu Shi, Yan Luximon
doaj +1 more source