Results 51 to 60 of about 113,837 (311)

Optimal blocked minimum-support designs for non-linear models

open access: yes, 2014
Finding optimal designs for experiments for non-linear models and dependent data is a challenging task. We show how the problem simplifies when the search is restricted to designs that are minimally supported; that is, the number of distinct runs ...
van de Ven, P.M., Woods, D.C.
core   +1 more source

Generating Improved Experimental Designs with Spatially and Genetically Correlated Observations Using Mixed Models

open access: yesAgronomy, 2018
The aim of this study was to generate and evaluate the efficiency of improved field experiments while simultaneously accounting for spatial correlations and different levels of genetic relatedness using a mixed models framework for orthogonal and non ...
Lazarus K. Mramba   +3 more
doaj   +1 more source

Unitary block designs

open access: yesJournal of Combinatorial Theory, Series A, 1974
AbstractGiven a projective plane E over the field of q2 elements and a unitary polarity π of E it is possible to construct the well-known unitary design U whose points are the absolute points of π and whose blocks are the non-absolute lines of π.
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Recursive Construction of Resolvable Nested Block Designs

open access: yesMathematics
This paper proposes a recursive method for constructing intra-resolvable balanced incomplete block designs (BIBDs). The approach exploits the algebraic and geometric structure of finite projective geometries over Galois fields to generate resolvable ...
Tariq S. Alshammari   +4 more
doaj   +1 more source

Mating plans for breeding trials using generalized row-column designs

open access: yesThe Indian Journal of Agricultural Sciences, 2021
Generalized Row-Column (GRC) designs are used where there is more than one unit in each row-column intersection. Mating plan is a systematic procedure of producing the progenies. Diallel and triallel crosses are some examples of mating plans.
ANINDITA DATTA   +5 more
doaj   +1 more source

On blocking sets in a design

open access: yesDiscrete Mathematics, 1997
A 2-\((\nu,k, \lambda)\) design \(D ...
openaire   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Balanced incomplete-block designs

open access: yes, 2022
Block designs are useful in experimental design when the experimental material is not uniform but can be divided into homogeneous blocks. Typically, blocks cannot contain all the treatments, so incomplete block designs are used. The condition of balance,
Cameron, Peter J.
core   +1 more source

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