Results 61 to 70 of about 102,634 (265)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Secretory phospholipase A2 (sPLA2) is an inflammatory mediator linked to acute chest syndrome (ACS) in sickle cell disease (SCD), a serious complication that can develop during an acute vaso‐occlusive pain episode (VOE). Plasma sPLA2 levels have been proposed as a potential biomarker for predicting ACS onset.
Rawan Korman +10 more
wiley +1 more source
Generalization of Wei's urn design to unequal allocations in sequential clinical trials
Contemporary Clinical Trials Communications, 2016 Wei's urn design was proposed in 1987 for subject randomization in trials comparing m≥2 treatments with equal allocation. In this manuscript, two modified versions of Wei's urn design are presented to accommodate unequal allocations.
Wenle Zhao, Viswanathan Ramakrishnan
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Symmetric Balanced Incomplete Block Designs (Sbibd) And Construction of Hadamard Rhotrices [PDF]
MATEC Web of ConferencesBalanced Incomplete Block Designs (BIBD) are the designs obtained from the arrangement of symbols in blocks following established rules and satisfying relevant necessary conditions.
Manivilasam Madhusoodanan Nair +2 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Estimating and Testing Augmented Randomized Complete Block Designs: The Neutrosophic Approach [PDF]
Neutrosophic Sets and SystemsIn plant breeding programs, the augmented design is designated to screen numerous new treatments compared with a few check treatments, which in turn are required to estimate both of error variance and local control for new future treatments.
Abdulrahman AlAita +2 more
doaj +1 more source
Compressed Sensing Based Non-Orthogonal Pilot Designs for Multi-Antenna Grant-Free Access Systems
IEEE Open Journal of the Communications Society, 2020 Grant-free access is an attractive approach to enable spectrum-efficient low-latency access for systems with massive number of users. Pilot design plays a crucial role for grant-free access as it needs to provide a large number of access codes with fast ...
Ayon Quayum, Hlaing Minn
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source