Results 81 to 90 of about 113,837 (311)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Symmetric Balanced Incomplete Block Designs (Sbibd) And Construction of Hadamard Rhotrices [PDF]

MATEC Web of Conferences
Balanced Incomplete Block Designs (BIBD) are the designs obtained from the arrangement of symbols in blocks following established rules and satisfying relevant necessary conditions.
Manivilasam Madhusoodanan Nair, Kalyan Rao H., Nijhawan Ginni   +2 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Circular designs balanced for neighbours at distances one and two

, 2014
Date of Acceptance: 23/05/2014We define three types of neighbour-balanced designs for experiments where the units are arranged in a circle or single line in space or time.
Aldred, R E L, Bailey, R. A., Mckay, Brendan D., Wanless, Ian, Wanless, Ian M., Aldred, R. E. L., Bailey, R A, McKay, Brendan   +7 more
core   +1 more source

Estimating and Testing Augmented Randomized Complete Block Designs: The Neutrosophic Approach [PDF]

Neutrosophic Sets and Systems
In plant breeding programs, the augmented design is designated to screen numerous new treatments compared with a few check treatments, which in turn are required to estimate both of error variance and local control for new future treatments.
Abdulrahman AlAita, Hooshang Talebi , Yasser Al Zaim   +2 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

EXPLORATION OF FINITE GROUP APPROACH IN BALANCED INCOMPLETE BLOCK DESIGN

Academy Journal of Science and Engineering
The development of block designs continues to be an unresolved challenge in combinatorial design, with several forms, the most notable being the balanced incomplete block designs (BIBDs).
Ukeme Akra, Anthony A. Isaac, Itoro T. Michael, Uwem A. Akapn   +3 more
doaj   +1 more source

3-Homogeneous Groups and Block-Transitive 7–(v, k, 3) Designs

Mathematical and Computational Applications, 2017
The classification of a block-transitive designs is an important subject on algebraic combinatorics. With the aid of MATLAB software, using the classification theorem of 3-homogeneous permutation groups, we look at the classification problem of block ...
Xiaolian Liao, Guohua Chen, Shangzhao Li
doaj   +1 more source

Compressed Sensing Based Non-Orthogonal Pilot Designs for Multi-Antenna Grant-Free Access Systems

IEEE Open Journal of the Communications Society, 2020
Grant-free access is an attractive approach to enable spectrum-efficient low-latency access for systems with massive number of users. Pilot design plays a crucial role for grant-free access as it needs to provide a large number of access codes with fast ...
Ayon Quayum, Hlaing Minn
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source