Results 71 to 80 of about 729,697 (285)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Ree groups as automorphism groups of block designs
Examples and CounterexamplesA recent classification of flag-transitive 2-designs with parameters (v,k,λ) whose replication number r is coprime to λ gives rise to eight possible infinite families of 2-designs, some of which are with new parameters.
Ashraf Daneshkhah
doaj +1 more source
Optimal Design of Block Quay Walls
Frontiers in Built Environment, 2020 Block walls, consisting of stacked unreinforced prefabricated concrete blocks, are commonly used for the construction of quay walls in the presence of rocky subgrades.
Stijn Francois +4 more
doaj +1 more source
On balanced incomplete block designs with specified weak chromatic number
, 2013 A weak $c$-colouring of a balanced incomplete block design (BIBD) is a colouring of the points of the design with $c$ colours in such a way that no block of the design has all of its vertices receive the same colour.
Horsley, Daniel, Pike, David A.
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
A Regular D‑optimal Weighing Design with Negative Correlations of Errors
Acta Universitatis Lodziensis. Folia Oeconomica, 2019 The issues concerning optimal estimation of unknown parameters in the model of chemical balance weighing designs with negative correlated errors are considered. The necessary and sufficient conditions determining the regular D‑optimal design and some new
Małgorzata Graczyk, Bronisław Ceranka
doaj +1 more source
Low energy and area efficient quaternary multiplier with carbon nanotube field effect transistors
ETRI Journal, 2021 In this study, new multiplier and adder method designs with multiplexers are proposed. The designs are based on quaternary logic and a carbon nanotube field‐effect transistor (CNTFET). The design utilizes 4 × 4 multiplier blocks.
Saeed Rahmati +2 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Generalization of Wei's urn design to unequal allocations in sequential clinical trials
Contemporary Clinical Trials Communications, 2016 Wei's urn design was proposed in 1987 for subject randomization in trials comparing m≥2 treatments with equal allocation. In this manuscript, two modified versions of Wei's urn design are presented to accommodate unequal allocations.
Wenle Zhao, Viswanathan Ramakrishnan
doaj +1 more source