Results 121 to 130 of about 731,157 (280)

Fully Polarimetric SAR Image Filtering by Combining Block Matching and Lee Filter

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Speckle filtering is a key preprocessing approach for the applications of polarimetric synthetic aperture radar (PolSAR) data. Most current PolSAR filtering algorithms can hardly get good balance in suppressing speckle and retaining image details.
Guisheng Zhao, Shengyuan Zhu, Yinglei Wu
doaj   +1 more source

Neural Nearest Neighbors Networks

open access: yes, 2018
Non-local methods exploiting the self-similarity of natural signals have been well studied, for example in image analysis and restoration. Existing approaches, however, rely on k-nearest neighbors (KNN) matching in a fixed feature space.
Plötz, Tobias, Roth, Stefan
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Sensitivity Analysis of Cumulative Oil Production and Production Rate on Block Heights and Capillary Continuity for an Iranian Carbonated Fractured Reservoir [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2009
Block heights and capillary continuity between matrix blocks play paramount role in the sensitivity analysis and therefore the history matching of cumulative oil production and production rate of carbonated fractured reservoirs.
Zahra Riazi, Fariborz Rashidi
doaj  

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

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