Results 111 to 120 of about 1,775,833 (254)
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Fast Block-Matching Algorithms for High-Resolution Video Compression
In this work we propose, discuss, and evaluate fast block-matching algorithms for high-resolution video sequences (e.g. HDTV or SHDTV). Commonly used logarithmic block-matching algorithms (like e.g. TSS or NTSS) are designed for the use in low-resolution
Ch. Hufnagl, A. Uhl
core
Preprocessing Pipelines including Block-Matching Convolutional Neural Network for Image Denoising to Robustify Deep Reidentification against Evasion Attacks. [PDF]
Pawlicki M, Choraś RS.
europepmc +1 more source
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Block-Matching Algorithm Based on Dynamic Search Window Adjustment
Dynamic search window adjustment for block-matching algorithm(BMA) based on the block similarity to overcome the computational complexity of full search BMA is presented.
Hwang-Seok Oh +2 more
core
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Towards Automated Eye Diagnosis: An Improved Retinal Vessel Segmentation Framework Using Ensemble Block Matching 3D Filter. [PDF]
Naveed K +5 more
europepmc +1 more source
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Modeling Building Block Interdependency
The Building-Block Hypothesis appeals to the notion of problem decomposition and the assembly of solutions from sub-solutions. Accordingly, there have been many varieties of GA test problems with a structure based on building-blocks.
Richard Watson +6 more
core +1 more source
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source

