Results 61 to 70 of about 535,226 (278)
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
AN ORDER-P TENSOR MULTIPLICATION WITH CIRCULANT STRUCTURE
Research on mathematical operations involving multidimensional arrays or tensors has increased along with the growing applications involving multidimensional data analysis. The -product of order- tensor is one of tensor multiplications.
Itsar Mangngiri +2 more
doaj +1 more source
Determinants of block matrices with noncommuting blocks
15 pages, no ...
openaire +2 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
A comparative study on the self-assembled nanostructured morphology and the rheological and mechanical properties of four different triblock copolymers, based on poly(styrene-block-diene-block-styrene) and poly(styrene-block-diene-block-styrene) matrices,
doaj +1 more source
A block bidiangonal form for block companion matrices
Let \(L_ k(\lambda)=\lambda^ kI+\sum^{k-1}_{j=0}\lambda^ jA_ j\) be a matrix polynomial (so \(A_ 0,...,A_{k-1}\) are \(n\times n\) matrices with complex entries) with the companion matrix \[ C_ k = \left[\begin{matrix} 0&1&0&...&0 \\ 0&0&1&...&0 \\ \vdots&\vdots&\vdots&&\vdots \\ 0&0&0&...&1 \\ -A_ 0&-A1_ 1&&...&-A_{k-1} \end{matrix} \right].
Hernández, Vicente G. +1 more
openaire +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Block companion matrices, discrete-time block diagonal stability and polynomial matrices [PDF]
A polynomial matrix G(z )= Iz m −∑ m−1 i=0 Ciz i with complex coefficients is called discrete-time stable if its characteristic values (i.e. the zeros of detG(z)) are in the unit disc. A corresponding block companion matrix C is used to study discrete-time stability of G(z).
openaire +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Inequalities for partial determinants of accretive block matrices
Let A = [ A i , j ] i , j = 1 m ∈ M m ( M n ) $A=[A_{i,j}]^{m}_{i,j=1}\in \mathbf{M}_{m}(\mathbf{M}_{n})$ be an accretive block matrix. We write det1 and det2 for the first and second partial determinants, respectively.
Xiaohui Fu +2 more
doaj +1 more source

