Results 141 to 150 of about 1,052,390 (266)

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

open access: yesFEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

On maximum residual block Kaczmarz method for solving large consistent linear systems

open access: yesAIMS Mathematics
In this paper, we propose two block variants of the Kaczmarz method for solving large-scale consistent linear equations $ Ax = b $. The first method, named the maximum residual block Kaczmarz (denoted as MRBK) method, first partitions the coefficient ...
Wen-Ning Sun, Mei Qin
doaj   +1 more source

An adaptive blocking strategy for matrix factorizations

open access: yes, 1990
On most high-performance architectures, data movement is slow compared to floating-point (in particular, vector) performance. On these architectures block algorithms have been successful for matrix computations. By considering a matrix as a collection of submatrices (the so-called blocks) one naturally arrives at algorithms that require little data ...
Philippe G. Lacroute, Christian Bischof
openaire   +3 more sources

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

open access: yesFEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Lipschitz estimate for elliptic equations with oscillatory coefficients

open access: yesAIMS Mathematics
Regularity for elliptic equations with oscillatory coefficients was concerned. Problem domains were periodic and consisted of a connected region with normal permeability and a disconnected matrix block subset with high permeability.
Li-Ming Yeh
doaj   +1 more source

The off-diagonal block of a PPT matrix

open access: yesLinear Algebra and its Applications, 2015
Abstract We give an operator inequality involving the off-diagonal block of a positive partial transpose matrix and the geometric mean of its diagonal blocks. Some new eigenvalue inequalities are derived, nicely completing the existing ones.
openaire   +2 more sources

Genetic diversity and population structure of the Taigan dog breed

open access: yesFEBS Open Bio, EarlyView.
The Taigan is a rare sighthound from the mountains of Kyrgyzstan. We used DNA markers to study its genetic diversity and compare it with other sighthound breeds. Our findings show that the Taigan shares close genetic ties with the Kazakh Tazy, suggesting a common ancestry shaped by nomadic traditions and regional adaptation.
Kira Bespalova   +10 more
wiley   +1 more source

Approximate Schur Complement Preconditioners for Half-Quadratic Image Restoration With Zero Boundary Conditions

open access: yesJournal of Mathematics
In this paper, the additive half-quadratic image restoration problem with zero boundary conditions is investigated. The Newton method is used to solve this problem and a structured linear system needs solving at each step.
Chaojie Wang   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy