Results 81 to 90 of about 5,909,835 (371)

A Note on the Eigenvalue Analysis of the SIMPLE Preconditioning for Incompressible Flow

Journal of Applied Mathematics, 2012
We consider the SIMPLE preconditioning for block two-by-two generalized saddle point problems; this is the general nonsymmetric, nonsingular case where the (1,2) block needs not to equal the transposed (2,1) block, and the (2,2) block may not be zero ...
Shi-Liang Wu, Feng Chen, Xiao-Qi Niu
doaj   +1 more source

Estimation of Gaussian Bi-Clusters with General Block-Diagonal Covariance Matrix and Applications [PDF]

, 2023
Anastasiia Livochka, Ryan P. Browne, Sanjeena Subedi   +2 more
openalex   +1 more source

Vague Block Matrix

, 2018
In this paper the idea t of vague matrix is extended in the field of vague block matrix and discussed some of their relational operations on vague block matrices.
openaire   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Computing the Exponential of Large Block-Triangular Block-Toeplitz Matrices Encountered in Fluid Queues

, 2015
The Erlangian approximation of Markovian fluid queues leads to the problem of computing the matrix exponential of a subgenerator having a block-triangular, block-Toeplitz structure.
Bini, D. A., Dendievel, S., Latouche, G., Meini, B.   +3 more
core   +1 more source

Preconditioning of two-by-two block matrix systems with square matrix blocks, with applications [PDF]

Applications of Mathematics, 2017
Two-by-two block matrices of special form with square matrix blocks arise in important applications, such as in optimal control of partial differential equations and in high order time integration methods. Two solution methods involving very efficient preconditioned matrices, one based on a Schur complement reduction of the given system and one based ...
openaire   +1 more source

Block minimal bases ℓ-ifications of matrix polynomials [PDF]

Linear Algebra and its Applications, 2019
The standard way of solving a polynomial eigenvalue problem associated with a matrix polynomial starts by embedding the matrix coefficients of the polynomial into a matrix pencil, known as a strong linearization. This process transforms the problem into an equivalent generalized eigenvalue problem.
Froilán M. Dopico, Javier Pérez, Paul Van Dooren   +2 more
openaire   +4 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Equivalent analysis of different estimations under a multivariate general linear model

AIMS Mathematics
This article explores the mathematical and statistical performances and connections of the two well-known ordinary least-squares estimators (OLSEs) and best linear unbiased estimators (BLUEs) of unknown parameter matrices in the context of a multivariate
Bo Jiang, Yongge Tian
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source