Results 91 to 100 of about 789,882 (293)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

MONITORING OF VARIOUS TYPES OF NEUROMUSCULAR BLOCKADE

open access: yesВестник анестезиологии и реаниматологии, 2018
Goal of the review: to build up the current understanding of electrophysiological specific features of various neuromuscular blockades. Having analyzed the results of multiple studies devoted to investigation of the impact of various medications ...
N. V. Chubchenko, K. M. Lebedinskiy
doaj   +1 more source

Does deep neuromuscular blockade during laparoscopy procedures change patient, surgical, and healthcare resource outcomes? A systematic review and meta-analysis of randomized controlled trials.

open access: yesPLoS ONE, 2020
BACKGROUND:Deep neuromuscular blockade may facilitate the use of reduced insufflation pressure without compromising the surgical field of vision. The current evidence, which suggests improved surgical conditions compared with other levels of block during
Amit D Raval   +8 more
doaj   +1 more source

The Addition Spectrum of a Lateral Dot from Coulomb and Spin Blockade Spectroscopy

open access: yes, 2000
Transport measurements are presented on a class of electrostatically defined lateral dots within a high mobility two dimensional electron gas (2DEG).
Ciorga, M.   +7 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Cotunneling and non-equilibrium magnetization in magnetic molecular monolayers

open access: yes, 2007
Transport and non-equilibrium magnetization in monolayers of magnetic molecules subject to a bias voltage are considered. We apply a master-equation approach going beyond the sequential-tunneling approximation to study the Coulomb-blockade regime.
Carsten Timm   +5 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

I’m blocking because... – Students’ motivations for participating in the student protest in serbia in 2024/2025.

open access: yesPolitičke Perspektive
The current student (and civil) protest in Serbia started at the end of November 2024, as a reaction to the fall of the canopy of the Railway station in Novi Sad, during which sixteen people lost their lives.
Jovana Čikić, Ana Bilinović Rajačić
doaj   +1 more source

Two-Photon Blockade in an Atom-Driven Cavity QED System

open access: yes, 2017
Photon blockade is a dynamical quantum-nonlinear effect that occurs in driven systems with an anharmonic excitation ladder. For a single atom strongly coupled to an optical cavity, we show that driving the atom gives a decisively larger optical ...
Hamsen, Christoph   +3 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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