Results 61 to 70 of about 560,572 (303)
Russia’s Blockade in the Sea of Azov: A Call for Relief Shipments for Mariupol [PDF]
, 2022 Blog post in EJIL:Talk! - Blog of the European Journal of International Law. Source at https://www.ejiltalk.org/russias-blockade-in-the-sea-of-azov-a-call-for-relief-shipments-for-mariupol/.On 24 February 2022, the Russian Federation launched an ...
Lott, Alexander
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Immune checkpoint modulation: Tenets and implications in glioblastoma
Glioma, 2019 Glioblastoma (GBM) is the most common primary central nervous system tumor, and despite advances made in traditional chemotherapy and radiation, it continues to carry a poor prognosis.
John P Lynes +4 more
doaj +1 more source
Comparison of epidural levobupivacaine and bupivacaine in lower abdominal and lower limb surgeries
Bali Journal of Anesthesiology, 2020 Background: Bupivacaine, the most commonly used drug for a central neuraxial blockade, also carries undesirable effects like a prolonged postoperative motor blockade.
Jay Prakash +5 more
doaj +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Checkpoint Blockade in Cancer Immunotherapy: Squaring the Circle [PDF]
, 2015 Manipulating the complex interaction between the immune system and tumour cells has been the focus of cancer research for many years, but it is only in the past decade that significant progress has been made in the field of cancer immunotherapy resulting
Maria A.V. Marzolini +2 more
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PharmaceuticalsBackground/Objectives: A systematic review was conducted to compile all the evidence on the impact of ADRB1 and ADRB2 genetic variants on the response to β-blockers, used for the management of cardiovascular diseases.
Houwaida Abbes +4 more
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
, 2023 Anesthesia providers are responsible for administering neuromuscular blocking agents, monitoring the level of blockade, and ensuring adequate reversal of these medications prior to extubation of surgical patients.
Romagnoli, Jenn +1 more
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