Results 61 to 70 of about 498,550 (314)
Comparison of epidural levobupivacaine and bupivacaine in lower abdominal and lower limb surgeries
Bali Journal of Anesthesiology, 2020 Background: Bupivacaine, the most commonly used drug for a central neuraxial blockade, also carries undesirable effects like a prolonged postoperative motor blockade.
Jay Prakash +5 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Monitoring of sedation during neuroaxial blockade.
, 2013 Errores del documento original. Autores: Guerrero OrriachJose Luis. Afiliación: PostgraduateResearch, Universidad Autónoma de Madrid, Facultad de Medicina, Spain. HospitalInfanta Leonor, Madrid, Spain.
Blanco, Brezo del +4 more
core +1 more source
PharmaceuticalsBackground/Objectives: A systematic review was conducted to compile all the evidence on the impact of ADRB1 and ADRB2 genetic variants on the response to β-blockers, used for the management of cardiovascular diseases.
Houwaida Abbes +4 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Russia’s Blockade in the Sea of Azov: A Call for Relief Shipments for Mariupol [PDF]
, 2022 Blog post in EJIL:Talk! - Blog of the European Journal of International Law. Source at https://www.ejiltalk.org/russias-blockade-in-the-sea-of-azov-a-call-for-relief-shipments-for-mariupol/.On 24 February 2022, the Russian Federation launched an ...
Lott, Alexander
core
Symmetries and Synchronization Blockade
, 2022 Synchronization blockade refers to an interferometric cancellation of quantum synchronization. In this manuscript, we show how the choice of synchronization measure and Hamiltonian symmetries affect the discussion of synchronization blockade.
Solanki, Parvinder +3 more
core +1 more source