Results 111 to 120 of about 194,544 (300)

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

Edge blockage in a 19-pin sodium-cooled bundle. [LMFBR]

open access: yes, 1977
To assess the effect of partial flow blockages on the local temperature distributions in LMFBR fuel assemblies, several experiments have been carried out at the Thermal-Hydraulic Out-of-Reactor Safety (THORS) Facility at the Oak Ridge National Laboratory.
Han, J. T.   +3 more
core  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Distinguishing Micromobility and Blockage in 6G Sub-THz Systems: A Machine Learning Approach

open access: yesIEEE Open Journal of the Communications Society
Dynamic human body blockage and user equipment (UE) micromobility in the hands of a user are two impairments that may lead to connectivity losses in 5G millimeter wave (mmWave, 30-100 GHz) and 6G sub-terahertz (sub-THz, 100-300 GHz) systems.
Humayra Anjumee Jeba   +2 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Spherical wave blockage in reflector antennas

open access: yes, 1997
The effects of the spherical wave blockage in reflector antennas is investigated. This problem is likely to occur in axially symmetrical feed antennas of single- and dual-reflector type in both single- and dual-reflector configurations, owing to the ...
Mizzoni, R.   +4 more
core   +1 more source

Meta analysis of application of positive pressure connector in infusion with superficial venous indwelling needle infusion

open access: yesHuli yanjiu, 2017
To probe into the difference between the incidence of blocked tubes and the incidence of phlebitis in patients with superficial venous catheter when using positive pressure connector and heparin cap joint.Methods:China Wanfang database,CNKI database(CNKI)
范燕华, 王春燕, 刘重斌
doaj  

Field Evaluation of 5G mmWave Relays in Various Topologies: NLOS Coverage Enhancement and Tolerance Against Blockage

open access: yesIEEE Access
As time progresses, the use of higher frequencies becomes increasingly necessary due to the growing issue of frequency congestion. While discussions are ongoing regarding the potential use of millimeter-wave (mmWave) frequencies introduced in 5G for the ...
Naoya Okubo   +8 more
doaj   +1 more source

Canalicular Blockage [PDF]

open access: yesAustralian and New Zealand Journal of Ophthalmology, 1973
openaire   +2 more sources

Home - About - Disclaimer - Privacy