Results 111 to 120 of about 194,544 (300)
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Edge blockage in a 19-pin sodium-cooled bundle. [LMFBR]
To assess the effect of partial flow blockages on the local temperature distributions in LMFBR fuel assemblies, several experiments have been carried out at the Thermal-Hydraulic Out-of-Reactor Safety (THORS) Facility at the Oak Ridge National Laboratory.
Han, J. T. +3 more
core
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Distinguishing Micromobility and Blockage in 6G Sub-THz Systems: A Machine Learning Approach
Dynamic human body blockage and user equipment (UE) micromobility in the hands of a user are two impairments that may lead to connectivity losses in 5G millimeter wave (mmWave, 30-100 GHz) and 6G sub-terahertz (sub-THz, 100-300 GHz) systems.
Humayra Anjumee Jeba +2 more
doaj +1 more source
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Spherical wave blockage in reflector antennas
The effects of the spherical wave blockage in reflector antennas is investigated. This problem is likely to occur in axially symmetrical feed antennas of single- and dual-reflector type in both single- and dual-reflector configurations, owing to the ...
Mizzoni, R. +4 more
core +1 more source
To probe into the difference between the incidence of blocked tubes and the incidence of phlebitis in patients with superficial venous catheter when using positive pressure connector and heparin cap joint.Methods:China Wanfang database,CNKI database(CNKI)
范燕华, 王春燕, 刘重斌
doaj
As time progresses, the use of higher frequencies becomes increasingly necessary due to the growing issue of frequency congestion. While discussions are ongoing regarding the potential use of millimeter-wave (mmWave) frequencies introduced in 5G for the ...
Naoya Okubo +8 more
doaj +1 more source

