Results 91 to 100 of about 194,544 (300)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

150 ICGA Journal September 2004 BLOCKAGE DETECTION IN PAWN ENDGAMES

, 2008
In this article 4 we introduce a blockage-detection method, which manages to detect a large set of blockage positions in pawn endgames, with practically no additional overhead.
Omid David, S. Netanyahu, Tabibi Ariel, Felner Nathan   +3 more
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Manipulation of Colloidal Flocbots for Flow Control

Nano Select
Localized control of blood flow is essential for vascular therapies but current embolization strategies often rely on invasive catheter‐based delivery of passive embolic agents.
Aaron K. Ishiki, Trevor D. Tong, David W. M. Marr   +2 more
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Decision Support System for Blockage Management in Fire Service

, 2014
In this article we present the foundations of a decision support system for blockage management in Fire Service. Blockage refers to the situation when all fire units are out and a new incident occurs.
Krasuski Adam, Kreński Karol
core   +1 more source

Physiological blockage in plants in response to postharvest stress [PDF]

, 2016
Flowers have been designed primarily for cutting because of the diversity of shapes, colors and also durability. However, ornamental plants are used in floral arrangements in vases and have limited shelf-life.
Silva, Luzia Ferreira da, Santos, Caio Marcio Guimarães, Souza, Angela Vacaro de, Paes, Reinaldo de Alencar, Vieira, Marcos Ribeiro da Silva   +4 more
core   +1 more source

The Positive and Negative Effects of Green Space on PM_2.5 Concentrations: A Review

Atmosphere
Fine particulate matter (PM2.5) can have considerable negative effects on human health. An increasing number of scholars are finding that green space can not only decrease PM2.5 levels but also exacerbate PM2.5 levels.
Junyou Liu, Bohong Zheng, Jiawei Li
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source